15 citations,
December 2020 in “International journal of molecular sciences” Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.
15 citations,
September 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” Skin doctors should recognize and treat conditions like hair-pulling and skin-picking early, often using therapy and medication, to help 50-70% of patients.
11 citations,
August 2013 in “International Journal of Cosmetic Science” The study suggests that a new protease inhibitor can make hair harder to pull out, potentially reducing hair loss.
5 citations,
September 1986 in “Pediatric Dermatology” A family showed a new condition with inherited hair loss and skin changes, possibly due to one genetic disorder.
2 citations,
April 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
2 citations,
June 2011 in “Journal of clinical and experimental investigations” Oral zinc sulphate is an effective and safe treatment for thallium poisoning, especially for skin and hair symptoms.
December 2018 in “IntechOpen eBooks” Neurohormones help control skin health and could treat skin disorders.
6 citations,
December 2015 in “International journal of nanomedicine” Using sonophoresis can make it harder for certain drug-loaded liposomes to get through the skin.
63 citations,
April 2005 in “Mechanisms of development” Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.
23 citations,
June 2016 in “FEBS Journal” Boosting β-catenin signaling in certain skin cells can enhance hair growth.
11 citations,
June 2017 in “Asian-Australasian journal of animal sciences” Fox genes are important for hair growth and development in cashmere goats.
1 citations,
September 2005 in “Oncology times” Wearing a frozen glove during chemotherapy can reduce nail and skin problems but may not be comfortable for everyone.
7 citations,
June 2021 in “Cell Proliferation” Low oxygen levels improve the function of hair and skin cells when they are in direct contact.
9 citations,
February 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.
23 citations,
December 2020 in “Frontiers in Cell and Developmental Biology” Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
16 citations,
November 2020 in “International journal of pharmaceutics” Using longer PEG chains helps nanoparticles penetrate hair follicles better, improving drug delivery for conditions like alopecia.
1 citations,
October 2019 in “International journal of contemporary pediatrics” A 12-year-old boy with twenty nail dystrophy, a condition affecting all nails, was treated conservatively due to its self-limiting nature and good prognosis.
34 citations,
June 2005 in “Developmental dynamics” Runx3 helps determine hair shape.
421 citations,
April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
34 citations,
July 2020 in “American journal of human genetics” Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.
24 citations,
January 2018 in “Development” Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.
2 citations,
December 2021 in “Pharmaceutics” Finasteride-loaded proniosomes effectively promote hair growth in mice.
2 citations,
February 2014 in “Hair therapy & transplantation” Alopecia Areata is an autoimmune condition causing hair loss, influenced by genetics, environment, and possibly improved by anti-MIF therapy, with many patients experiencing regrowth within a year.
January 2024 in “Cosmetics” Menopause worsens skin, hair, and nails, affecting self-esteem and quality of life.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.
Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.
Any medication can cause skin reactions, some due to allergies and others due to dosage or genetic factors.
7 citations,
July 2019 in “Advances in preventive medicine” Most diabetic patients have skin problems, which are more common with longer diabetes duration and poor blood sugar control.
4 citations,
July 2015 in “Case Reports in Dermatology” A woman with unexplained hair loss was found to have harmless skin tumors and a scarring hair loss condition, but the tumors didn't cause the hair loss.
19 citations,
December 2015 in “Journal of Investigative Dermatology” The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.