Hypotrichosis and Alopecia

July 2019

DABVP Ryane E. Englar

hypotrichosis alopecia genetic factors endocrine factors inflammatory factors behavioral factors atopic dermatitis vasculitis follicular dysplasia chemotherapy-induced alopecia hormone supplementation skin scrapes Wood's lamp fluorescence hair loss skin scrape Wood's lamp

TLDR Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.

The document "Hypotrichosis and Alopecia" from 2019 reviewed various causes and manifestations of hair loss in both humans and animals, focusing on genetic, endocrine, inflammatory, and behavioral factors. It highlighted specific conditions such as atopic dermatitis, vasculitis, and follicular dysplasia in animals, and chemotherapy-induced alopecia in both humans and animals. The document emphasized the importance of thorough diagnostic approaches, including history taking, pattern recognition, and specific diagnostic methods like skin scrapes and Wood's lamp fluorescence. It also discussed treatment options ranging from hormone supplementation to managing underlying conditions and mitigating secondary infections, underscoring the impact of these conditions on quality of life and the importance of accurate diagnosis and tailored treatment strategies.

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research Novel Insights Into the Pathways Regulating the Canine Hair Cycle and Their Deregulation in Alopecia X

18 citations , October 2017 in “PLOS ONE”

The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.

research Long-Term Management with Adipose Tissue-Derived Mesenchymal Stem Cells and Conventional Treatment in a Dog with Hepatocutaneous Syndrome

21 citations , August 2017 in “Journal of veterinary internal medicine”

Combining amino acid and stem cell therapy may help manage hepatocutaneous syndrome in dogs.

research Treatment of Alopecia X with Medroxyprogesterone Acetate

10 citations , September 2013 in “Veterinary dermatology”

Medroxyprogesterone injections caused hair regrowth in some dogs with alopecia X.

research Canine Noninflammatory Alopecia: A Comprehensive Evaluation of Common and Distinguishing Histological Characteristics

28 citations , May 2012 in “Veterinary Dermatology”

Different types of dog hair loss are linked to problems starting the hair growth phase and early hair cycle ending.

research Chemotherapy-Induced Hair Loss

48 citations , August 2010 in “PubMed”

Chemotherapy often causes hair loss, which is distressing for many, but usually reversible.

research Disorders Causing Focal Alopecia

1 citations , January 2008 in “Elsevier eBooks”

The document concludes that various disorders can cause hair loss in dogs, each requiring different treatments, and some may heal on their own.

research Hair Loss Pattern Due to Chemotherapy-Induced Anagen Effluvium: A Cross-Sectional Observation

53 citations , January 2007 in “Dermatology”

Chemotherapy often causes patterned hair loss, with some scalp areas more resistant to hair loss than others.

research An Overview on Congenital Alopecia in Domestic Animals

32 citations , November 2006 in “Veterinary dermatology”

Congenital alopecia in domestic animals is rare and involves abnormal hair follicle development, needing better understanding and classification.

research Comparative Dermatology: Canine Endocrine Dermatoses

34 citations , July 2006 in “Clinics in dermatology”

Endocrine diseases in dogs often cause skin problems, with hypothyroidism and hyperadrenocorticism being common and leading to hair loss and infections.

research The Cat With Alopecia

1 citations , January 2006 in “Elsevier eBooks”

Cats lose fur due to various reasons, including allergies, infections, genetics, hormones, diet, cancer, stress, and some conditions are treatable while others are not.

research Atrophic Diseases of the Adnexa

15 citations , July 2005

The document's conclusion cannot be provided because the document is not readable or understandable.

research Adrenal Steroid Hormone Concentrations in Dogs with Hair Cycle Arrest (Alopecia X) Before and During Treatment with Melatonin and Mitotane

52 citations , October 2004 in “Veterinary dermatology”

Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.

research Behavioral Dermatology

39 citations , March 2003 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice”

Behavioral dermatology treats skin problems by considering both emotional and physical factors.

research Follicular Dysplasia in Five Weimaraners

18 citations , October 2002 in “Veterinary dermatology”

Five Weimaraners had a milder form of color dilution alopecia causing hair loss and skin issues.