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Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Improved dermabrasion techniques in 1987 led to better treatment results for skin issues like acne scars.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Using defensins to activate stem cells may improve skin aging signs without causing inflammation.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

FAI values above 6.4 may suggest high androgen levels and increased metabolic risks in Chinese women of reproductive age.

Skin cell-derived vesicles can help heal skin injuries effectively.

Acne is caused by increased sebum, abnormal skin shedding, bacteria, and inflammation, not dirt; treatments vary from creams to antibiotics or isotretinoin, with severe cases needing a dermatologist's care.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.

Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.

Men with higher androgen levels may have severe COVID-19 symptoms, but those on antiandrogen therapy are less likely to contract the virus and have milder symptoms. Anti-androgen drugs could potentially treat COVID-19, but more research is needed.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.

Malassezia infection may cause refractory acne, and antifungal treatments can help.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Hair follicles create different cell layers and proteins, controlled by various molecules.

TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.

Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.

Hair growth is cyclic and influenced mainly by local factors.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

Hair cortisol levels can show increased stress during late pregnancy but only for up to six months.