research Characterization of an Autoimmune Condition Associated with AEC Syndrome
Controlling Tslp can improve health in AEC syndrome patients.
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630-660 / 1000+ resultsresearch Prevention of Murine Sclerodermatous Chronic Graft-Versus-Host Disease by Rapamycin
Rapamycin increased survival in mice with severe chronic graft-versus-host disease by expanding regulatory T cells.
research Dermatological Diseases from a Genetic Perspective
New gene discoveries have improved diagnosis and treatment for skin and hair disorders, but more research is needed to fully understand them.
research Betaine Supplementation Is Less Effective Than Methionine Restriction in Correcting Phenotypes of CBS Deficient Mice
Methionine restriction works better than betaine for treating CBS deficiency symptoms in mice.
research Macrophage Ferroportin Is Essential for Stromal Cell Proliferation in Wound Healing
Macrophage iron release is crucial for hair growth and wound healing.
research The Secretory Clear Cell of the Eccrine Sweat Gland as the Probable Source of Excess Sweat Production in Hyperhidrosis
Eccrine sweat gland's clear cells likely cause excessive sweating in hyperhidrosis.
research PKC Downregulation Upon Rapamycin Treatment Attenuates Mitochondrial Disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research Overexpression of Spermidine/Spermine N1-Acetyltransferase Under the Control of Mouse Metallothionein I Promoter in Transgenic Mice: Evidence for a Striking Post-Transcriptional Regulation of Transgene Expression by a Polyamine Analogue
Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.
research Hairless-Knockout Piglets Generated Using CRISPR/Cas9 Exhibit Abnormalities in Skin and Thymus
Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.
research Increased Proliferation of Epidermal Gamma Delta T Cells and Expression of the Transmembrane Protein, BST2, in Alopecia Areata
BST2 protein and certain T cells increase in early alopecia areata.
research A Therapeutic Role for Survivin in Mitigating the Harmful Effects of Ionizing Radiation
Inducing survivin in normal tissues can protect against radiation damage.
research Cisd2 Deficiency Impairs Neutrophil Function by Regulating Calcium Homeostasis via Calnexin and SERCA
Lack of Cisd2 disrupts calcium balance in cells, leading to poorly functioning neutrophils.
research The Effect of Topical Gel Secretome Hypoxic Mesenchymal Stem Cells on IL-6 and TGF-β Gene Expression in Male Wistar Alopecia-Like Rat Models Induced by Fluconazole
SH-MSCs gel reduced IL-6 and increased TGF-β, suggesting it could treat alopecia.
research Effect of Topical Gel Administration of Secretome Hypoxia Mesenchymal Stem Cells on IL-10 and TNF-α Gene Expression: An In Vivo Experimental Study in Male Wistar Rats with Fluconazole-Induced Alopecia
SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.
research Estimating Scalp Moisture In A Hat Using Wearable Sensors
A hat with sensors can measure scalp moisture well, helping with hair care.
research P120-Catenin Regulates Epidermal Inflammation in a Cadherin-Dependent Manner
p120-catenin helps control skin inflammation by regulating cadherin levels.
research Effect of Saengbal-Eum Topical Application on Hair Growth Promotion in C57BL/6 Mice
Saengbal-eum promotes hair growth similarly to Minoxidil and could be used for alopecia treatment.
research Neuroimmunology of Stress: Skin Takes Center Stage
Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
research Alopecia Areata in Aging C3H/HeJ Mice
Alopecia areata in these mice is inherited, more common in young females, and can be treated with triamcinolone acetonide.
research Transfollicular Drug Delivery: Is It a Reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research Trichotillomania: Neurobiology And Treatment
Trichotillomania involves hair pulling and can be treated with therapy and medication.
research Prodrugs of Butyric Acid from Bench to Bedside: Synthetic Design, Mechanisms of Action, and Clinical Applications
New butyric acid prodrugs show promise for cancer treatment, anemia management, and protecting hair from chemotherapy damage.
research Oral Retinoids in Dermatology
Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
research Levetiracetam in the Treatment of Idiopathic Generalized Epilepsies
Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.
research IL-36γ Drives Skin Toxicity Induced by EGFR/MEK Inhibition and Commensal Cutibacterium Acnes
A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
research Group IID, IIE, IIF, and III Secreted Phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Use of Induced Pluripotent Stem Cells in Dermatological Research
iPSCs can help treat genetic skin disorders by creating healthy skin cells from a small biopsy.
research Applications of Marine Organism-Derived Polydeoxyribonucleotide: Its Potential in Biomedical Engineering
PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.
research Immunotherapeutic Effects of Allogeneic Mesenchymal Stem Cells on Systemic Lupus Erythematosus
Early treatment with the right dose of stem cells can reduce lupus symptoms.
research Topical Antiandrogens
Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.