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Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

A specific genetic change is linked to mental disorders, intellectual disability, and possibly autoimmune disease in a family.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Epigenetic mechanisms control skin development by regulating gene expression.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.

Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.

Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.

MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.

Blocking miR-27a increases sheep hair follicle stem cell growth and decreases cell death, which could help improve wool quality and treat hair loss.

MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.

Some people with chronic hair loss may have thyroid autoimmunity.

Maternal aspartame consumption during pregnancy leads to skin damage and higher apoptosis in newborn rat offspring.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Non-coding RNAs are crucial for skin development and health.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Pro-IGF-II improves muscle repair in old mice.

Maize hybrids show better early growth due to complex gene interactions from their parent strains.

Dental pulp stem cells might not reliably become neurons.

The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.

Non-coding RNAs could help detect and treat radiation damage.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.