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The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Finasteride helps female-pattern hair loss.

Restoring immune privilege in hair follicles could help treat certain types of hair loss.

The skin's bacteria might influence the development of a hair loss condition called alopecia areata.

Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.

Use minoxidil for hair loss treatment, and finasteride for men.

New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Genomic approach finds new possible treatments for hair loss.

A 14-year-old girl with severe hair loss regrew her hair using upadacitinib.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Muse cells keep their special features and can become different cell types even after being frozen and thawed three times.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

Neurohormones help control skin health and could treat skin disorders.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.