25 citations,
May 1994 in “Journal of Investigative Dermatology” Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.
11 citations,
September 2019 in “Dermatologic Surgery” A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.
[object Object] 185 citations,
August 2005 in “Autoimmunity Reviews” Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.
30 citations,
October 2016 in “Current research in translational medicine” Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.
10 citations,
May 1978 in “Acta Dermato Venereologica” Pustules in toxic erythema are linked to hair follicles or sweat ducts.
149 citations,
April 2004 in “Journal of Dermatological Science” Minoxidil boosts hair growth by increasing cell production and survival.
36 citations,
November 2009 in “Journal of Investigative Dermatology” Prolactin may affect hair growth differently based on gender and scalp area.
1 citations,
April 2018 in “Journal of Investigative Dermatology” People respond differently to hair loss treatment with PRP because of individual differences in growth factors from platelets.
6 citations,
January 2016 in “Methods in molecular biology” Scientists have developed a new method using stem cells to grow and transplant hair follicles, which could be useful for hair regeneration treatments.
16 citations,
April 2021 in “Frontiers in Cell and Developmental Biology” New hair follicles could be created to treat hair loss.
11 citations,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.
10 citations,
February 2016 in “Journal of Dermatological Science” Skin sheath cells help in hair growth and renewal after birth.
4 citations,
March 2014 in “The FASEB Journal” The HIF-2α/ARNT complex is important for hair follicle development by controlling cell growth.
[object Object] March 2022 in “Book Publisher International (a part of SCIENCEDOMAIN International)” Human hair has bipolar electrical charges due to gaps in the hair follicle's electromagnetic fields.
January 2022 in “Stem cell biology and regenerative medicine” Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
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August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
161 citations,
August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
138 citations,
June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
130 citations,
December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle melanocytes die during hair regression.
106 citations,
September 2010 in “Stem cells” Skin-derived precursors in hair follicles come from different origins but function similarly.
85 citations,
January 2018 in “Cell stem cell” Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
71 citations,
November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Edar signaling is crucial for proper hair follicle development and function.
43 citations,
December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
43 citations,
December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
36 citations,
May 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
36 citations,
October 2015 in “Cell reports” Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
35 citations,
January 2017 in “Journal of Dermatological Science” Stress can cause early aging in certain skin cells, leading to problems with hair growth.
11 citations,
March 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific group of skin stem cells was found to help maintain hair follicle cells.
11 citations,
June 2012 in “Acta histochemica” Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.
10 citations,
August 2021 in “EMBO Reports” The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.