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The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Researchers found 15 new genetic links to skin traits in Japanese women.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Autophagy is crucial for normal sebaceous gland function and sebum composition.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.

Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.

Epidermal stem cells don't use gap junctions to communicate.

NK cells play a role in skin diseases like eczema and psoriasis.

CD98hc's role in skin health decreases with age.

Lymphatic vessels are important for skin repair and could affect skin disease treatments.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

FLCN helps control iron levels in cells.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.