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GLI2 increases follistatin production in human skin cells.

Desmoglein 4 is controlled by specific proteins that affect hair growth.

Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.

Inflammation helps stem cells repair tissue by directing their behavior.

SOX9 is essential for the development of various organs and hair follicles.

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.

Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

The exact identity of skin stem cells and how skin cells differentiate is not fully known.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

Wnt-3a helps grow more skin stem cells, which could lead to new hair loss treatments.

New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

Hydrogel scaffolds can help wounds heal better and grow hair.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Stem cell self-renewal is complex and needs more research for full understanding.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.