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TGFβ signaling prevents sebaceous gland cells from producing fats.

Less differentiated melanoma cells are more vulnerable to a type of cell death, which could improve cancer treatments.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Certain vitamins in wrong amounts, alcohol abuse, metals, and other toxins can cause serious brain and nerve damage.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Markers help differentiate between apocrine and eccrine sweat glands to identify sweat gland tumors.

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

17β-estradiol can reduce inflammation in the skin.

Methotrexate is not proven to maintain remission in ulcerative colitis.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.

Non-coding RNAs could help detect and treat radiation damage.

Sirtuin 1 could be a potential drug target for treating hypertrophic scars.

Oxidative stress is higher in women with PCOS, especially if they're obese, and it may increase their risk of heart disease.

Blue light therapy is safe for skin and may protect against UV radiation.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Carbon dots show promise for tissue repair and growth but need more research to solve current challenges.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Minoxidil's absorption is too variable for it to be a reliable reference drug.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

Excessive blue light harms eye cells and disrupts sleep patterns.

Meis2 is essential for touch sensation and nerve function in mice.