research Techniques for the Discovery and Evaluation of Drugs Against Alopecia
We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.
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research Transcriptional Control of Epidermal Stem Cells
Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
research Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1
Vitexin Compound 1 may help reduce skin aging caused by UVA light.
research Zinc Therapy in Dermatology: A Review
Zinc is effective for treating various skin conditions, including warts and acne.
research Somatic Stem Cell Heterogeneity: Diversity in the Blood, Skin, and Intestinal Stem Cell Compartments
Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
research Melanogenesis Is Coupled to Murine Anagen: New Concepts for the Role of Melanocytes and Regulation of Melanogenesis in Hair Growth
Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.
research Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles
EGF makes hair follicles grow longer but stops hair production.
research The Hair Growth Promoting Effect of Asiasari Radix Extract and Its Molecular Regulation
Asiasari radix extract promotes hair growth and increases protein synthesis and cell proliferation.
research Ferreting Out Stem Cells From Their Niches
New methods have greatly improved our understanding of stem cell behavior and roles in the body.
research Induction of Dark Keratinocytes by 12-O-Tetradecanoyl-Phorbol-13-Acetate and Mezerein as an Indicator of Tumor-Promoting Efficiency
TPA is about 50 times more effective at promoting tumors than MZ.
research Chrousos Syndrome: From Molecular Pathogenesis to Therapeutic Management
The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.
research Estrogens and Human Scalp Hair Growth: More Questions Than Answers
The effects of estrogen on human hair growth are unclear and need more research.
research TGF-β2 Is Specifically Expressed in Human Dermal Papilla Cells and Modulates Hair Folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
research Combination of Herbal Extracts and Platelet-Rich Plasma Induced Dermal Papilla Cell Proliferation: Involvement of ERK and Akt Pathways
Herbal extracts and platelet-rich plasma together may help increase hair growth by making certain cells grow more, through specific cell growth pathways.
research A Cell-Based System for Screening Hair Growth-Promoting Agents
Apigenin may help promote hair growth and could treat hair loss.
research Dormancy in the Stem Cell Niche
Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
research Adenosine Stimulates Growth of Dermal Papilla and Lengthens the Anagen Phase by Increasing the Cysteine Level via Fibroblast Growth Factors 2 and 7 in an Organ Culture of Mouse Vibrissae Hair Follicles
Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.
research Minoxidil Specifically Decreases the Expression of Lysine Hydroxylase in Cultured Human Skin Fibroblasts
Minoxidil reduces lysine hydroxylase in skin cells.
research A Topical Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor Antagonist Stimulates Hair Growth in Mice
A cream with a specific hormone blocker increases hair growth in mice.
research Polyphenols from the Heartwood of Cercidiphyllum Japonicum and Their Effects on Proliferation of Mouse Hair Epithelial Cells
Extracts from Cercidiphyllum japonicum wood can stimulate mouse hair cell growth like common hair growth treatments.
research Minoxidil
Minoxidil effectively treats hair loss, works better for women, and requires consistent use.
research The HPV16 Oncogenes Cause Aberrant Stem Cell Mobilization
HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
research Selective Inhibition by Minoxidil of Prostacyclin Production by Cells in Culture
Minoxidil stops cells from making prostacyclin, which may help with hair growth. More research is needed.
research Major Depletion of SOX2+ Stem Cells in the Adult Pituitary Is Not Restored and Does Not Affect Hormonal Cell Homeostasis and Remodeling
The pituitary gland functions normally even after losing most SOX2+ stem cells.
research The Stumptailed Macaque as a Model for Baldness: Effects of Minoxidil
Minoxidil promotes hair regrowth in early baldness stages and prevents baldness in non-bald scalps.
research Chrysanthemum Zawadskii Extract Induces Hair Growth by Stimulating the Proliferation and Differentiation of Hair Matrix
Chrysanthemum zawadskii extract helps hair grow by stimulating hair cells.
research Evidence That Mirex Promotes a Unique Population of Epidermal Cells That Cannot Be Distinguished by Their Mutant Ha-ras Genotype
Mirex seems to promote a unique group of skin cells different from those affected by another tumor promoter, TPA.
research Secretory Phospholipase A2-IIA Overexpressing Mice Exhibit Cyclic Alopecia Mediated Through Aberrant Hair Shaft Differentiation and Impaired Wound Healing Response
Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
research Conceptual Basis for Use of Chemotherapeutic Agents and Their Pharmacology
The conclusion is that effective cancer treatment often requires a combination of therapies, but must be carefully managed due to serious side effects and the risk of immunosuppression.
research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.