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The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Laser device increases hair density, safe for treating hair loss in men and women.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

BMP2 and BMP7 have opposite roles in feather formation.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

The document concludes that understanding and treating hair loss requires recognizing its various types and using appropriate diagnostic tools and treatments.

Nude mice with grafted human skin developed scars similar to human hypertrophic scars.