21 citations
,
February 2023 in “Pharmaceuticals” This study reports that extracts from pomegranate leaves contain bioactive compounds with antioxidant, antimicrobial, and skin-beneficial properties, suggesting their potential use in nutraceutical and cosmeceutical applications.
February 2024 in “International Journal of Scientific Research in Science and Technology” This literature review outlines the traditional uses, nutritional composition, and bioactive compounds of pomegranate plants, highlighting their varied pharmacological actions such as antibacterial, antiviral, anticancer, and antioxidant effects, and discusses the peel's chemical composition and toxicology.
3 citations
,
January 2021 in “Jurnal Health Sains” This study describes the demographic distribution of seborrheic dermatitis patients in Banda Aceh, identifying an increase in male prevalence from 2016 to 2019 and varied age group prevalence across the years.
41 citations
,
June 2023 in “Antioxidants” This review highlights that pomegranate exhibits promising beneficial effects in preclinical and clinical studies for cardiovascular and non-cardiovascular diseases, though further research is needed on its bioavailability and metabolites for effective therapeutic use.
April 2026 in “Inflammopharmacology” This study found that Punica granatum ethanolic leaf extract may alleviate skin fibrosis in rats by modulating inflammation-related pathways and reducing dermal alterations.
This monograph reviews the historical and contemporary use of pomegranate in medicine, detailing its chemical components and applications across various medical fields including oncology, dentistry, and urology.
15 citations
,
April 2022 in “Biointerface Research in Applied Chemistry” This review presents current evidence on medicinal plants and their phytoconstituents, such as phenolic compounds, used in acne treatment, highlighting their potential as alternatives to conventional therapies due to issues like antibiotic resistance and high cost.
January 1980 in “Lluc: revista de cultura i d'idees” This study found that Agaricus bisporus-derived β-Glucan particles showed potential as an anticancer, antimicrobial, and antioxidant agent, inducing apoptosis and disrupting mitochondrial membrane potential in cervical cancer HeLa cells.
28 citations
,
October 2023 in “Trends in biotechnology” 13 citations
,
April 2021 in “International Journal of Molecular Sciences” This study found that the fermented black soybean product GR-SC65 reduced particulate matter-induced cell death and oxidative stress in A549 cells, suggesting potential as a therapeutic agent for lung injury prevention.
2 citations
,
January 2017 in “Plant” This study found that in vitro extracts of Glycyrrhiza glabra root are strong antioxidants, particularly in ethanolic form, and contain secondary metabolites, but only showed mild antibacterial activity.
June 2024 in “International journal of biological macromolecules” This study reports that beta-glucan hybrid hydrogels, reinforced with laponite nanoclay, showed promising results in rat models for managing hemorrhage and diabetic wound healing by enhancing hemostasis, reducing inflammation, and promoting faster wound closure and tissue regeneration.
March 2022 in “Benha Journal of Applied Sciences” This study found that serum PGRN levels and HOMA-IR were significantly higher in male AGA patients compared to controls, suggesting a link to insulin resistance and metabolic syndrome.
9 citations
,
April 2019 in “Food Chemistry” This study developed an efficient method for converting polymeric procyanidins into high-purity oligomeric procyanidins using a semisynthetic approach combined with separation techniques.
28 citations
,
March 2020 in “Journal of ethnopharmacology” This study found that ginsenoside Rb1 treatment significantly reduced aging symptoms in mice by regulating cell cycle and apoptotic pathways, potentially linked to metabolic changes.
2 citations
,
January 2023 in “Bioresource Technology Reports” This study suggests that using glycosidases to lyse the polysaccharides of Botryoccocus braunii may allow for the semi-continuous recovery of hydrocarbons while keeping the cells viable.
2 citations
,
May 2025 in “ACS Food Science & Technology” This review examined recent biotechnological advances, including micropropagation and in vitro culture techniques, aimed at enhancing the production of beneficial metabolites in pomegranates, highlighting unexplored biosynthetic pathways and key enzymes involved in compound synthesis.
September 2025 in “Journal of Applied Biological Chemistry” In a laboratory study, Grateloupia elata extract demonstrated antioxidant and anti-aging effects by scavenging free radicals, inhibiting collagenase and elastase, increasing procollagen production, and reducing MMP-1 secretion, suggesting its potential use in functional cosmetics.
2 citations
,
September 2022 in “Cellular and molecular biology” In this study, Agaricus bisporus derived β-Glucan particles demonstrated antimicrobial, antioxidant, and anticancer effects against cervical cancer HeLa cells, suggesting potential as a therapeutic option.
March 2025 in “Dental Journal (Majalah Kedokteran Gigi)” This study developed a biodegradable gelatin and chitosan hemostatic sponge, enhanced with pomegranate peel extract, for dental applications, highlighting its effective antibacterial properties, improved blood absorption, and reduced clotting time, suggesting potential for use in clinical dental and wound care procedures.
7 citations
,
December 2008 in “Journal of Dermatological Science” Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.
December 2025 in “Scientific Reports” In this laboratory study, α-mangostin was found to significantly reduce melanin content and downregulate pigmentation-related genes in cultured skin and B16F10 cells, suggesting potential application as a natural whitening agent in sunscreen development.
64 citations
,
October 1998 in “Acta dermato-venereologica” This study found that proanthocyanidins from grape seeds significantly promote hair follicle cell proliferation and hair cycle transition in mice, suggesting their potential as hair growth agents.
January 2025 in “Catalysts” This study investigated the production of β-cyclodextrin from ginkgo seeds, finding that a pretreatment scheme involving high-temperature gelatinization significantly improved the conversion rate to 72.63%, highlighting the industrial potential of underutilized ginkgo seed powder for sustainable applications.
This research reports that transglucosylation significantly improved the water solubility of baicalin through the synthesis of baicalin glucosides, with BG1 and BG2 showing enhanced solubility and potential biological activity similar to baicalin in antioxidant and anti-glycation assays.
3 citations
,
June 2024 in “Pharmacia” In this study, isatin-gallate hybrids were synthesized and assessed, with compound 3b showing significant in vitro antioxidant and cytotoxic activities, and the series displaying moderate efficacy in inhibiting coronavirus activity through in silico analysis.
14 citations
,
November 2013 in “Journal of the American Society for Horticultural Science” This study observed that glycine inhibited root growth and stimulated root hair development in habanero pepper seedlings, with ethylene signaling suggested to mediate these effects.
April 2017 in “Advances in Tissue Engineering & Regenerative Medicine Open Access” This study found that hydro alcoholic extract from the stem of Musa paradisiacal inhibited alpha amylase and alpha glucosidase enzymes in vitro, suggesting potential antidiabetic benefits.
In this study, applying a 5% concentration of pomegranate peel extract significantly enhanced hair growth on male rabbits, showing results comparable to the positive control using 2% Minoxidil, but higher concentrations or lower concentrations did not perform as well.
28 citations
,
November 2020 in “Polymers” This study found that crosslinking buffalo gelatin with different methods can modify its properties and potential as a skin substitute, though double-crosslinking may increase immunogenicity slightly.