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This study found that GPC1 plays a crucial role in regulating angiogenesis in human dermal microvascular endothelial cells, which may make it a potential target in alopecia treatment research.

This study found that the 15-PGDH inhibitor DPP improved endothelial function in hair-related cells exposed to DHT by reducing oxidative stress and enhancing angiogenic capacity.

This study found that calcitonin‐gene‐related peptide immunoreactive sensory axons in rats are predominantly involved in tissue maintenance rather than nociceptive functions.

The study observed that mRAGE expression is prevalent in keratinocytes of the healthy human epidermis and may regulate inflammation and apoptosis to maintain skin homeostasis rather than responding to aging processes.

In this study, researchers used the CRISPR/Cas9 system to edit the FGF5 gene in Dorper sheep, observing increased density and finer wool, along with changes in cortisol levels and antioxidant enzyme activity linked to hair follicle development.

Overexpressing the epigen gene in mice leads to enlarged sebaceous glands and greasy fur.

This study observed that inducible deletion of the Ugcg gene in mouse epidermis led to a significant reduction in GlcCers and epidermal POS-Cers, causing impaired skin barrier function and delayed wound healing.

This study found that prostaglandin receptors are widely expressed in hair follicles, suggesting a complex network of prostanoid pathways involved in hair growth control.

This study found that activating TRPV4 in the skin of mice induced hair follicle regeneration by promoting anagen transition, suggesting potential treatment strategies for hair loss.

This study found that Egyptian women with frontal fibrosing alopecia had lower serum PPARγ levels and a higher occurrence of PPARG gene polymorphism compared to healthy controls, suggesting a potential role for PPARγ in the condition's development.

In this study, researchers explored various aspects of the TRPV3 ion channel, including its novel mechanosensitivity to shear stress, and identified novel agonists while investigating how repeated stimulation affects TRPV3 activity, but found no evidence of GPCRs sensitizing the channel.

This study found that phosphorus and nitrogen deprivation increased root hair length in Brassica carinata and induced the expression of certain P-responsive genes, such as LRR and PRP.

This study found that Epiprofin acts as a negative regulator of parathyroid hormone transcription, with potential implications for controlling PTH production in hyperparathyroidism.

This study showed that a 2-kilobase upstream region of the mouse keratin 17 gene enables targeted GFP expression in major epithelial appendages of transgenic mice, indicating sonic hedgehog's involvement in its regulation.

This study reported that ginseng had a superior therapeutic effect on benign prostatic hyperplasia in rats, showing nearly normal histological architecture compared to finasteride's incomplete restoration.

This study observed that intrauterine and early postnatal exposure to finasteride affected prostatic development in Mongolian gerbils, with significant sex-based differences, particularly higher alterations in female prostates.

Progesterone reduces anxiety without needing progesterone receptors.

This study found that ginsenoside Rg3 significantly inhibited melanogenesis in human melanocytes and B16F10 cells by activating the ERK pathway, suggesting potential as a skin-whitening agent.

This study found that finasteride may affect Ca 2+ signalling in human sperm by interacting with the PGE 1 -binding site, but its impact on fertilization requires further investigation.

This study found that the GPR39 receptor plays a novel role in accelerating wound healing in mouse skin, although it is not essential for skin development or homeostasis.

This study demonstrated that dominant mutations in mouse gasdermin A3 disrupt mitochondrial oxidative stress regulation, suggesting a gain-of-function effect on epidermal differentiation.

This study reports that the dye peri-xanthenoxanthene (PXX) can act as an efficient photocatalyst for various radical reactions, including complex dual catalytic processes and the synthesis of an investigational drug intermediate.

This review discusses the various roles of skin-resident dermal white adipose tissue in hair growth inhibition, antibacterial responses, and wound healing, reporting no new empirical findings.

This study suggests that the progesterone metabolite allopregnanolone and progesterone regulate distinct gene sets involved in glioblastoma cell proliferation, with some overlapping effects modified by finasteride.

This study reports that GLP-1 receptors and proglucagon are expressed in the skin of newborn mice, with GLP-1 potentially playing a role in skin development and hair follicle formation.

In this study, finasteride was found to potentiate stress-induced disruption in sensory gating of rats by neutralizing the increase in allopregnanolone levels after acute stress.

This study found that the mammalian Hr protein can interact with the p53 pathway by binding to a specific p53 response element, influencing the regulation of genes involved in cell cycle control.

This study provides a comprehensive platform to explore stem cell interactions regulating hair follicle growth, revealing key signaling pathways in epithelial-mesenchymal interactions using advanced RNA sequencing and transgenic reporters.

This study found that PRC2 plays a crucial role in maintaining intestinal homeostasis by supporting progenitor cell proliferation and limiting secretory lineage differentiation.

In this study, researchers identified gremilin-2 as a highly specific gene to the dermal sheath cup, suggesting it plays a key role in maintaining its properties.