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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.

Agmatine may help reduce seizures linked to hormone changes in female rats.

The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.

The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.

A postmenopausal woman's excess male hormone symptoms improved after her ovaries were removed.

GnRH analogue can help diagnose ovarian causes of high testosterone in postmenopausal women when scans don't show the cause.

Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.

Balancing treatment effectiveness with side effects is crucial for relapsed follicular non-Hodgkin's lymphoma, especially in older patients.

Dutasteride reduces hospitalization and prostate cancer risk compared to finasteride, potentially offsetting its higher cost.

Deslorelin implants successfully treated hair loss in two male Keeshonden dogs.

PCOS is a complex condition linked to hormonal imbalance and insulin resistance, with weight loss being important for management.

Effective management of PCOS includes lifestyle changes, medication for menstrual regulation, fertility treatments, and cosmetic issue remedies.

Transgender patients in critical care need better-trained medical staff and specific guidelines.

Different PCOS subgroups have similar metabolic features, but those without menstrual problems have milder issues.

Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

About 15% of adolescent girls in a region of India have Polycystic Ovarian Syndrome, which is more common in those born by cesarean, with wisdom teeth, or with central obesity.

Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.