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New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Ectoin helps prevent cortisone-induced skin problems and supports skin health.

Long-term fluticasone treatment does not harm the immune system in horses with heaves.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

We need better ways to test and understand SARMs to make safer and more effective treatments.

The protein RSL4 is crucial for making root hairs longer by controlling genes related to cell growth.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.