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Adults with classic congenital adrenal hyperplasia value medication that prevents weight gain from glucocorticoids the most.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

The consensus provided guidelines for treating the Female Athlete Triad and a system to decide when athletes can return to sports.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Children and adults with Cushing's disease show different symptoms and males have more severe cases; surgery outcomes can be predicted by certain factors.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

SLE and DM can coexist but are rare and need careful evaluation.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Fermented soy protein may help prevent bone loss by affecting bone cell activity.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.