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Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Intense exercise at night can delay the body's internal clock gene expression by 2 to 4 hours.

Looking at skin can help find and treat serious diseases early.

The exact cause of growth hormone-responsive alopecia in dogs is unclear.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

The research suggests that autophagy-related genes might play a role in causing alopecia areata.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Dogs with generalized discoid lupus erythematosus have similar symptoms to humans and need continuous treatment.

Obesity increases the risk of skin infections, inflammatory conditions, and melanoma, but not basal cell carcinoma.

TGPC plus CGT is effective and safe for treating severe alopecia areata in children.

New drugs are improving treatment for hormone-related diseases in small pets.

DCP therapy causes side effects like weakness, flushing, headaches, and taste changes, but less frequently causes hypertension and diabetes.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Substance from human umbilical cord blood cells promotes hair growth.

Finasteride use can cause depression-like behavior in male rats.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

FAI values above 6.4 may suggest high androgen levels and increased metabolic risks in Chinese women of reproductive age.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Lactoferrin helps mice grow hair by increasing cell growth and hair follicle development.

Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

Obesity is linked to various skin disorders, which can help with early diagnosis and prevention of long-term health issues.

High and low doses of prednisolone helped 62% of children with severe alopecia regrow hair with some weight gain and mild acne as side effects.

Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.