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New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.

Lactate production is important for activating hair growth stem cells.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Goat reproductive activity and coat growth are affected by light and temperature, with temperature altering prolactin levels and hair growth, but not melatonin or estrus onset.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

Autophagy is crucial for normal sebaceous gland function and sebum composition.

GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.

Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.

Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.

Short daily photoperiods improve cashmere production in Inner Mongolia white cashmere goats.

Human sebaceous glands can grow back in skin grafts on mice and work like normal human glands.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Goat hair growth and follicle activity change with the seasons and differ between males and females.

Isoflavone may help manage PCOS symptoms, but its effectiveness is uncertain.

Female hair loss patients more likely to have dry eye and gland issues.

Sulfotransferase SULT1A1 activity may predict minoxidil treatment success for hair loss.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Thuja orientalis hot water extract may help hair grow by starting the growth phase and improving hair follicle development.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Hoxc13 is linked to seasonal hair growth in Cashmere goats and is affected by melatonin.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.

The interdigital gland in crossbred sheep is similar to skin and has specialized structures for secretion.