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Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.

Most pregnant women experience skin changes like darkening and stretch marks, and some may have skin conditions that usually get better after giving birth.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Pregnant women's hair gets thicker.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Eating isoflavone can help mice grow hair by increasing a growth factor.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Adults with certain skin conditions may have higher levels of inflammation in their body.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.