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Cancer development is like natural selection, involving mutated cells and environmental factors.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

SHBG may be a useful early indicator and treatment target for PCOS.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

Mothers and newborns with dental fillings had higher mercury in their hair, but getting fillings during pregnancy didn't raise mercury levels further.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

ECM molecules are crucial for hair growth and development.

EGF and FGF help hair growth by affecting cell differentiation and fiber growth.

Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.