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This study suggests that the expression patterns of keratin and filaggrin indicate milia may originate from the outermost cells of the hair bulge in the outer root sheath.

This study successfully established Tsc2-deficient embryonic stem cells from Eker rats and found these cells have distinct gene expression compared to non-mutant cells, which could help identify new therapeutic targets for TSC-related pathogenesis.

This study reported that reprogramming keratinocytes from plucked hair provides an easy, non-invasive, and efficient method for generating pluripotent iPSCs without the need for medical professionals or operating rooms.

This study reports improved methods for harvesting and processing keratinocytes from plucked human hair, enhancing their utility in generating donor-specific induced pluripotent stem cells more efficiently and reliably.

This article reviews the role of adult stem cells in tissue homeostasis and wound repair, focusing on their regulation within the murine hair follicle's specialized niche, but it presents no new findings.

This study found that human hair follicles can be used to generate induced pluripotent stem cells, which can then efficiently differentiate back into keratinocytes.

This study found that hair germ and epidermal basal cells differ in keratin expressions in rat hair tissues, with hair-specific keratins appearing after the differentiation of each layer.

In this study, bioengineered hair germ microspheres made from HME hydrogels promoted hair follicle regeneration in vivo, suggesting a promising approach for hair loss treatment.

Stem cells in developing hair follicles move to specific areas as they mature.

In a keratinocyte-specific knockout mouse model, this study found that deleting GRK2 disrupted hair follicle homeostasis, causing cyst-like structures, abnormal growth patterns, and eventual hair loss, suggesting potential links to immune-mediated alopecias.

This study found that hHbl gene expression is localized in the cortical cells of the human hair shaft and is notably high in pilomatricoma cells transitioning to hair shaft keratinocytes.

This study investigated the gene Col19a1, finding its expression is specific to certain cells during hair follicle development in mice, suggesting its potential role in hair follicle morphogenesis.

Basonuclin helps identify and track hair follicle development and cycling in mice.

This study found that prevelex coatings on microwell array devices enhanced the formation of uniform cell spheroids and enabled the development of hair follicles in tissue engineering applications.

Basonuclin is crucial for hair follicle development and cycling in mice.

This review summarizes recent advances in organoid technology for generating tissue models from the three germ layers and reports no new experimental results.

This review highlights similarities in the development of thymus and skin epidermis, reporting no new results; the authors emphasize shared molecular mechanisms despite different embryonic origins.

This study found that Fibroblast growth factor-9 (FGF-9) accelerates epithelial invagination in engineered ectodermal organs and suggests its potential role in organogenesis and regeneration research.

This study reports the successful generation of inducible pluripotent stem cells from mesenchymal stem cells derived from human hair follicles, marking a novel method of reprogramming these cells.

This review discusses the differentiation and reprogramming capabilities of both hematopoietic and non-hematopoietic stem cells and their significance for regenerative medicine; it reports no new experimental results.

This study found that mouse embryoid bodies adhered quickly and differentiated efficiently into cardiomyocytes on negatively charged poly(sodium p-styrene sulfonate) hydrogels, similar to their behavior on gelatin-coated polystyrene.

This study found that hair follicles can be used to generate pluripotent stem cells, which successfully differentiate into keratinocytes and may improve hair regeneration and grafting for medical applications.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.

This review discusses the multiple layers of environmental controls on hair stem cell homeostasis and suggests that targeting these layers could offer safer regenerative medicine therapies without directly using stem cells.

This review discusses the generation of germ cell-like cells from skin-derived stem cells and reports no new results; the potential for these cells to produce viable progeny remains unclear.

This narrative literature review examined how linking embryonic development with non-genetic skin anomalies can improve diagnostic accuracy, guide prenatal counseling, and enrich dermatology education by revealing specific vulnerabilities in skin morphogenesis and supporting advances in regenerative medicine.

This study found that their novel 3D-imaging method, ASAXA-μCT, identified shrinkage of sweat glands as a key factor in skin aging, which leads to dermal defects, decreased elasticity, and increased wrinkling and sagging.

This study demonstrated a method for large-scale preparation of self-sorted hair follicle germs in vitro, which successfully generated hair follicles when transplanted into the skin of nude mice.

This study found that while extracellular matrix components like hyaluronic acid promoted larger organoid formation, other matrix components hindered hair follicle germ assembly in an in vitro model.