Adult Stem Cells as an Alternative Source of Multipotential Cells in Regenerative Medicine

    April 2009 in “ Current stem cell research & therapy ”
    Selim Kuçi, Zyrafete Kuçi, Hatixhe Latifi-Pupovci, D. Niethammer, Rupert Handgretinger, Michael Schumm, Gernot Bruchelt, Peter Bader, Thomas Klingebiel
    TLDR Adult stem cells can become many different cell types, offering wide possibilities for repairing damaged tissues.
    The document discussed the potential of adult stem cells as an alternative to embryonic stem cells in regenerative medicine. It highlighted that adult stem cells, including tissue-specific and hematopoietic stem cells, could be reprogrammed under appropriate conditions to differentiate into a wide range of cell types. This ability was demonstrated in various sources such as skin, adipose tissue, cord blood, and bone marrow. The paper emphasized the significance of both hematopoietic (CD45+) and non-hematopoietic stem cells in contributing to different germ layers (endodermal, mesodermal, and neuroectodermal lineages), underscoring their importance for regenerative therapies.
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