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Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

Genetic discoveries are leading to new treatments for alopecia areata.

Differences in gene expression and methylation patterns found in AGA patients suggest potential targets for future treatments.

Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.

Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.

Researchers developed a cost-effective 66 K SNP chip for cashmere goats that is accurate and useful for genetic studies.

Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.

The study identified 12 potential biomarkers for hair loss and how they affect hair growth.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Less differentiated melanoma cells are more vulnerable to a type of cell death, which could improve cancer treatments.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Identified genes linked to male-pattern baldness may help develop new treatments.

Hair follicle stem cells change states with age, affecting hair growth and aging.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

Certain genes in Iranian sheep are linked to wool production and heat adaptation.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Certain circular RNAs are crucial for wool growth and curvature in goats.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Trichilemmal carcinoma shares genetic changes with other skin cancers, suggesting similar causes and potential treatments.

Two mutations in KRT74 and EDAR genes cause sheep to have finer wool.

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

ERG increases SOX9, promoting prostate cancer growth and invasion.

More research is needed to understand hair aging and develop effective treatments.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.