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Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.

Case-only trees and random forests improve predictions of treatment effects in clinical trials.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Mild exercise reduces pain in older rats through a brain chemical, while intense exercise reduces pain in all rats through a different pain-blocking process.

The study suggests that hypothyroidism may cause alopecia areata.

Vitamin D receptor is crucial for skin wound healing.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.

Rapamycin treatment helps reduce brain inflammation and symptoms of mitochondrial disease by blocking specific pathways in mice.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.

CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

The study found that variations in hair protein genes are likely due to evolutionary deletions or duplications.

Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

Platelet-rich Plasma Gel may help treat en coup de sabre scleroderma, improving symptoms and skin quality with minimal side effects.

Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Boreal caribou in northeastern British Columbia have significant health issues, including infections, tick infestations, and mineral deficiencies.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

A new gene mutation caused a man's rare skin condition, Schöpf-Schulz-Passarge syndrome.