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Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Skin problems can be linked to sexual abuse, requiring careful medical and psychological evaluation.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

Higher fluoride levels may delay puberty in boys.

Women with congenital adrenal hyperplasia have lower fertility, but with proper treatment, they can conceive successfully.

Medicinal plants are used to treat skin conditions, but more evidence is needed before recommending them widely.

Low selenium intake may delay puberty in boys but not in girls.

DSDs are birth conditions causing unusual sex development, managed with personalized care and sometimes surgery, but still lack a standard treatment approach.

People with Behçet's disease can develop life-threatening lung artery aneurysms that may require surgery.

The document concludes that respectful, gender-affirming healthcare improves mental health and encourages continued medical care for transgender and non-binary individuals.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.

Most postmenopausal women experience significant skin changes and various skin conditions.

The treatment helped a transgender woman stop drinking, improved her mental health, and reduced her gender dysphoria.

Doctors often miss Hair Tourniquet Syndrome, which can lead to serious damage if not treated quickly.

Men may experience long-term sexual dysfunction after stopping Finasteride.

Finasteride caused serious side effects and led to six suicides.

Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.

Finasteride use during early pregnancy may cause limb deformities in babies.

Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.

P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.

A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Searches for acne, hair loss, and eczema increased during COVID-19, while searches for other skin issues decreased.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Most insurance companies do not cover extra gender-affirming surgeries, with coverage being low and inconsistent.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

The document sets criteria for diagnosing long-term sexual dysfunctions caused by certain medications.