Imiquimod-Induced Effluvium After Intravaginal Application for Treatment of Cervical Intraepithelial Neoplasia

June 2019 in “ JAAD Case Reports ”

Carina Borst, Christoph Grimm, Adrian Tanew, Sonja Radaković

imiquimod telogen effluvium trichogram cervical intraepithelial neoplasia IMQ CIN

Studysummary This article discusses the use of imiquimod as a treatment for actinic keratosis, basal cell carcinoma, and human papillomavirus warts, noting both its therapeutic benefits and common side effects such as local inflammation and flu-like symptoms.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

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research Alopecia and Associated Toxic Agents: A Systematic Review

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This review summarizes existing studies on toxic agents that can cause alopecia, with thallium and colchicine having the most established links, while others like botulinum toxin A need further investigation.

research Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression

25 citations , July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that applying topical imiquimod during mid and late telogen in mice activates hair follicle stem cells and influences immune cell infiltration, promoting hair cycle entry independently of Wnt signaling.

research A Case of Imiquimod-Induced Alopecia

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Imiquimod cream can rarely cause temporary hair loss.

research A Case of Imiquimod-Induced Alopecia

6 citations , January 2009 in “Journal of Dermatological Treatment”

This case report suggests that imiquimod cream 5% may cause telogen effluvium as a rare side effect after treating actinic keratosis on the scalp.

research Drug-Induced Hair Loss and Hair Growth

147 citations , April 1994 in “Drug Safety”

Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.

research Telogen Effluvium: New Concepts and Review

69 citations , March 1993 in “Archives of Dermatology”

This article proposes five mechanisms for telogen effluvium based on changes in the follicular cycle, which are supported by clinical findings, highlighting the condition's diverse causes.

research Telogen Effluvium: A Comprehensive Review

214 citations , March 1993 in “Archives of Dermatology”

This article proposes five different mechanisms for telogen effluvium, supported by clinical findings, based on changes in different phases of the hair cycle.