Generalized Maculopapular Rash and Fever in Systemic Lupus Erythematosus

July 2023 in “ The Journal of Family Practice ”

Alexandra Verdieck

alopecia systemic lupus erythematosus hydroxychloroquine autoimmune disease chronic inflammation hair loss SLE Plaquenil

TLDR The man was diagnosed with lupus and improved with treatment.

A 29-year-old man presented with fever, rash, hair loss, joint pain, and other symptoms, leading to a diagnosis of systemic lupus erythematosus (SLE). The patient's symptoms included a generalized maculopapular rash, alopecia, and oral ulcers, with lab tests showing leukopenia, a high ANA titer, and positive anti-SM antibodies. SLE is an autoimmune disease causing chronic inflammation in multiple organ systems, with dermatologic findings in over 70% of cases. The patient was treated with hydroxychloroquine and low-dose steroids, showing improvement. SLE diagnosis requires a combination of clinical and laboratory criteria, and treatment may involve immunosuppressive therapy.

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