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Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Non-surgical procedures can help reduce wrinkles and stimulate skin repair by understanding skin aging at the molecular level.

Human skin xenografting could improve our understanding of skin development, renewal, and healing.

Higher miR-34a levels and the A variant of the MIR-34A gene are linked to increased risk and severity of alopecia areata.

Certain immune-related proteins are higher in people with alopecia and their healthy relatives, hinting at a genetic link.

The zinc finger protein 3 in Arabidopsis thaliana reduces plant growth and root hair development.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.

Notch signalling helps skin cells differentiate and prevents tumors.

Mutations in the P2RY5 gene cause hereditary woolly hair.

The paper concludes that breast cancer treatment involves complex interactions between medical symptoms, patient experiences, and commercial influences, requiring a holistic approach.

Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.

The supplement highlighted advancements and challenges in plastic and reconstructive surgery, including the impact of smoking, chemotherapy, and new treatments like Tafluprost for hair loss.

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.

Certain medications and maintaining adequate iron levels can help manage women's hair loss.

A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.

New treatments for common hair loss are needed.

The study found that the protein Dkk4 helps regulate hair growth by controlling Wnt signaling in mice.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

PCOS may increase the risk of certain cancers.

Abnormal gene expression related to keratin causes hair loss in certain mice.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

Hair follicle development in cashmere goats involves dynamic changes in proteins and metabolites, with key roles for oxytocin, MAPK, and Ca2+ pathways.

Proteins with added sugars are crucial for plant root hair growth.

ECM1-modified stem cells can effectively treat liver cirrhosis.

Different types of stem cells help maintain and heal skin.

Three-dimensional culture helps dermal papilla cells grow new human hair follicles.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.