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Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Epigenetic mechanisms control skin development by regulating gene expression.

Chromosomal changes, including those in the WRN gene and rDNA, may significantly contribute to aging.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Alopecia areata involves immune response and gene changes affecting hair loss.

Low iron levels may be linked to some types of hair loss in women.

Some people with the skin color loss condition, vitiligo, also develop the skin inflammation condition, lichen planus, possibly due to local trauma, sun damage, or genetic factors.

Advancements in hair biology include new treatments and tools for hair growth and alopecia.

Early hair loss may indicate risk of insulin resistance.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

A specific gene variant is linked to a higher risk of hair loss from chemotherapy in breast cancer patients.

Biotechnology could lead to new hair growth products.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

A certain genetic variation in the IL1A gene may lower the risk of a hair loss condition in Chinese people.

Genetic manipulations that extend lifespan in mice may not work as effectively in humans.

Dissecting cellulitis of the scalp is a condition that causes inflammation and scarring on the scalp, mainly affecting African-American men, and can lead to permanent hair loss.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.

Genes affect cytokine production, which can influence chronic diseases, and certain interventions may help prevent related molecular damage.

Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Male-pattern hair loss is largely influenced by genetics, with key genes identified.

Antiviral medication valganciclovir may improve skin and hair in Trichodysplasia Spinulosa patients.