research Toll-Like Receptor 4 (TLR4): New Insights into Immunity and Aging
TLR4 is important in aging-related diseases and could be a new treatment target.
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research The Epithelial Stem Cell Niche in Skin
Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
research Premature Aging Syndromes: From Patients to Mechanism
Studying premature aging syndromes helps understand human aging and suggests potential treatments.
research Candidate SNP Markers of Reproductive Potential Predicted by Significant Change in Affinity of TATA-Binding Protein for Human Gene Promoters
Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
research Pathophysiology of Behçet's Disease
Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.
research Insights Into the Scenario of SARS-CoV-2 Infection in Male Reproductive Toxicity
COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.
research The Phenotypic and Genotypic Spectra of Ichthyosis With Confetti Plus Novel Genetic Variation in the 3′ End of KRT10
Ichthyosis with confetti is a genetic skin disorder with consistent ectodermal malformations and various KRT10 gene mutations.
research Editors' Picks
Scientists found gene mutations that affect hair loss, skin stem cells, and skin disorders, and identified drugs that may help treat blood vessel and skin conditions.
research Addressing an Antiferromagnetic Memory
Researchers developed a new type of memory using antiferromagnets that is stable, not disrupted by magnets, and works at room temperature.
research Coexisting Trichorrhexis Nodosa and Pili Annulati: A Case Report of Hair Shaft Abnormalities in a Syrian Family
A 23-year-old Syrian woman has two rare hair disorders, and avoiding hair treatments plus using vitamins and minoxidil may help.
research Support for Dermatological Research in Sub-Saharan Africa: Insights from African Hair and Skin Research Programs
The document concludes that more local research on African skin and hair is needed despite increased scientific output from Sub-Saharan Africa.
research The Impact of Certain Genetic Variants (Single Nucleotide Polymorphisms) on Incidence and Severity of COVID-19
Certain genetic differences may affect how likely someone is to get COVID-19 and how severe it might be.
research Wound Healing: A Paradigm for Regeneration
Wound healing insights can improve regenerative medicine.
research Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration
The method quickly analyzes hair growth genes and shows that blocking Smo in skin cells stops hair growth.
research Exome-Wide Age-Of-Onset Analysis Reveals Exonic Variants In ERN1 And SPPL2C Associated With Alzheimer’s Disease
Researchers found two new genetic variants linked to Alzheimer's disease.
research Hormonal Regulation in Male Androgenetic Alopecia: Sex Hormones and Beyond - Evidence from Recent Genetic Studies
Hormones and genes affect hair growth and male baldness.
research Structural and Dynamic Insights into Substrate Binding and Catalysis of Human Lipocalin Prostaglandin D Synthase
The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.
research Comparative Transcriptome Profiling Provides New Insights Into Mechanisms of Androgenetic Alopecia Progression
AGA progression involves increased lipid synthesis, electron transport, and hair follicle miniaturization.
research Laser Therapies in Androgenetic Alopecia: Review and Clinical Experiences
Low-level laser therapy effectively improves hair growth in androgenetic alopecia with minimal side effects.
research Genotype Triad for HOTAIR rs10783618, LINC-ROR rs1942347, and MALAT1 rs3200401 as Molecular Markers in Systemic Lupus Erythematosus
Certain genetic markers can indicate higher or lower risk for systemic lupus erythematosus.
research A Genome-Wide Association Study Identified a Genetic Variant Associated With Hair Thinning in Japanese Women
A genetic variant linked to hair thinning in Japanese women was found.
research Enhancing Diagnostic Yield of Monogenic Diabetes Through Phenotypic and Molecular Reanalysis of 128 Individuals With Young Onset Hyperglycemia: Highlighting the Significance of Accurate Case Characterization
Combining genetic and physical trait analysis improves diagnosis accuracy for monogenic diabetes.
research Cellular and Molecular Characterization of Sebaceous Gland Self-Renewal and Regeneration Following Complete Genetic Ablation
The research found that a protein called PPARg is important for the formation and healing of sebaceous glands, which can regenerate independently from hair follicles.
research Investigating the Role of Various Extracellular Matrix in Androgenetic Alopecia: Insights from Immunostaining and Quantitative Analysis - A Pilot Study
ECM changes may play a role in hair loss, with differences between males and females.
research Mechanical Anisotropy of Hair Affected by Genetic Diseases Highlights Structural Information Related to Differential Crosslinking in Keratins
research Translational Frontiers: Insight From Lymphatics in Skin Regeneration
Lymphatic vessels are important for skin repair and could affect skin disease treatments.
research Atlas of Geriatric Dermatology
The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.
research Hormonal and Genetic Etiology of Male Androgenetic Alopecia
research Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets (HVDRR): Clinical Heterogeneity and Long-Term Efficacious Management of Eight Patients from Four Unrelated Arab Families with a Loss of Function VDR Mutation
Patients with the same genetic mutation for vitamin D-resistant rickets showed different symptoms but all improved with treatment except for hair loss.
research Ovarian Cancer Surgery: Heed This LION’s Roar
Removing lymph nodes does not improve survival for advanced ovarian cancer and may cause more complications.