research Hyperandrogenism in Polycystic Ovarian Syndrome and Role of CYP Gene Variants: A Review
Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.
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research Physiopathology and Current Treatments of Androgenetic Alopecia: Going Beyond Androgens and Anti-Androgens
Hair loss treatments work better with lifestyle changes.
research LPA3, A Unique G Protein-Coupled Receptor For Lysophosphatidic Acid
LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.
research Pili Torti: A Feature of Numerous Congenital and Acquired Conditions
Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.
research The Therapeutic Promise of Apoptosis
Blocking cell death in certain stem cells can improve wound healing and tissue regeneration.
research Markers of Peripheral Androgen Action In Vivo and In Vitro
Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.
research Hair Aging And Anti-Aging
Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
research Finasteride And Dutasteride In The Treatment Of Androgenetic Alopecia: Risk Or Benefit?
Finasteride and dutasteride may help prevent hair loss but could cause side effects like sexual dysfunction and psychological issues.
research Rare and Underappreciated Causes of Polycystic Ovarian Syndrome
Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.
research Darwinian Health and Other Contradictions
The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.
research Comments Concerning the Real Risk of Sexual Adverse Events Secondary to the Use of 5-Alpha-Reductase Inhibitors
The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.
research The Art of Repair in Surgical Hair Restoration—Part II
The document concludes that careful planning, efficient use of every hair graft, and setting surgical priorities are crucial for successful hair restoration surgery.
research Androgenetic Alopecia: Perspective from Patients in a Singaporean Tertiary Dermatology Center
Hair loss affects self-esteem; patients seek effective, low side-effect treatments.
research APCDD1 Is a Novel Wnt Inhibitor Mutated in Hereditary Hypotrichosis Simplex
A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
research Pathophysiological Mechanisms Implicated in Postpartum Depression
Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.
research Obesity and the Skin
Obesity is linked to various skin problems and may increase the risk of skin cancer.
research Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair
Fat cells in the skin help start healing and form important repair cells after injury.
research Polycystic Ovary Syndrome: Update on Diagnosis and Treatment
The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.
research Role of Genetics and Sex Steroid Hormones in Male Androgenetic Alopecia and Female Pattern Hair Loss: An Update
Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.
research Safety of Testosterone Treatment in Postmenopausal Women
Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
research Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia
Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
research Pattern Hair Loss in Men: Diagnosis, Genetic Link, Clinical Features, and Treatments
Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.
research A Neuroendocrinological Perspective on Human Hair Follicle Pigmentation
Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
research Menopause and Aging: Quality of Life and Sexuality
Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.
research Spatiotemporal Control of CRISPR/Cas9 Gene Editing
The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
research What Controls Hair Follicle Cycling?
The control system for hair growth cycles is not well understood and needs more research.
research The Human Skin Microbiome in Selected Cutaneous Diseases
Changes in skin microbes play a role in some skin diseases and could lead to new treatments.
research Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction
High levels of androgens during early development may cause PCOS-like symptoms.
research Hair Through the Female Life Cycle
Women's hair generally gets thinner and less dense starting in their mid-thirties, with hair loss becoming more common as they age due to both genetics and environment.
research Behavioral Dermatology
Behavioral dermatology treats skin problems by considering both emotional and physical factors.