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Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

A woman's chronic headaches and hair loss were cured by treating her syphilis.

The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Hair loss caused by longer latent hair cycle and sudden miniaturization, not gradual follicle size reduction.

Men with hair loss feel it affects their emotions and life quality, and want more effective treatments.

Actinic keratosis is a sun-induced skin condition that can potentially turn into skin cancer and requires various treatments to prevent this.

Actinic keratosis is a sun-induced skin condition that can potentially turn into skin cancer and requires treatment to prevent malignancy.

Four genes are potential markers for hair loss condition alopecia areata, linked to a specific type of cell death.

New insights into cell communication in psoriasis suggest innovative drug treatments.

Quadruple-coated probiotics significantly improve IBS symptoms.

Pica disorder in central Iraq is mainly found in females and is linked to low iron levels; treatment with iron improves most patients.

Robotic hair transplantation with AI offers more reliable, precise, and efficient hair restoration.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Long-COVID has diverse, long-term health impacts, especially in young people.

Videodermoscopy is effective for diagnosing different types of non-scarring hair loss.

Doctors in the Middle East need better treatments and more knowledge about new therapies for hair loss condition Alopecia Areata.

People with hidradenitis suppurativa are more likely to have bipolar disorder than those with psoriasis or without skin conditions.

Targeting NETs may help reduce fibrosis in Crohn's disease.

Higher antigliadin antibody levels are linked to alopecia areata severity.

The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.

No cure exists for alopecia areata, and treatments are personalized.

Mothers have more hair proteins than their children, with age-related differences in protein patterns, and some proteins in hair could indicate early childhood development.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

Dermal EZH2 controls skin cell growth and differentiation in mice.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

The weight loss drug Orlistat can cause liver damage and should be used with caution, especially in those with liver or kidney issues.

Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.

The document is a detailed guide on skin conditions and treatments for dermatologists.

Accurate diagnosis and timely, tailored treatments improve outcomes in obstetrics and gynecology.