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Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

The PIP5K1A gene helps cashmere growth in goats by promoting cell proliferation, and melatonin boosts its expression.

Blocking TRPV3 may help treat itch in dry skin conditions.

miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.

Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Scientists created stem cells that can grow hair and skin.

UV radiation causes skin cancer, but sunscreens and certain drugs can help prevent it.

Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.

LHX2 is essential for hair follicle development, controlled by NF-κB and TGFβ2 signaling.

Vitamin D Receptor is crucial for hair follicle shrinkage and cell death, affecting hair growth.

The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.

CRISPR/Cas9 gene-editing may effectively treat hair loss but requires more research for safe use.

Certain microRNAs are important for sheep hair follicle development and could help improve wool quality.

Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.

Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Changes in KRT17 gene activity linked to wool production in Angora rabbits.

The same genetic mutation in Sjögren-Larsson syndrome can lead to different levels of severity, suggesting other factors influence the symptoms.

Understanding hair biology is key to developing better treatments for hair and scalp issues.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.

The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.

Removing β-catenin in certain stem cells causes hair whitening and pigmentation issues.

Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.