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Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.

The document concludes that low-dose acne treatment is most suitable for moderate acne, with high patient satisfaction and low relapse rates.

Special fiber materials boost the healing properties of certain stem cells.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Advanced human skin models improve drug development and could replace animal testing.

Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Testosterone may slow down wound healing and increase inflammation.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Plant-based ingredients are effective and safe for modern skincare products.

Caffeine improves hair growth, thickness, and reduces shedding.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.