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The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

There is a significant need for better-validated quality of life tools in dermatology.

Four specific genes are linked to keloid formation and could be potential treatment targets.

Quercetin may help improve symptoms of polycystic ovary syndrome.

Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.

Certain gut bacteria may increase or decrease the risk of male pattern baldness.

HAIR & SCALP COMPLEX may help treat hair loss by stimulating hair growth and restarting the hair cycle.

The YH complex, made from Astragalus membranaceus and Cinnamomum cassia, may help treat hair loss by promoting hair growth and follicle development.

New skin lesions on the scrotum or vulva in patients with a history of internal cancer could indicate rare skin metastasis.

Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.

Onions may help reduce cancer risk and obesity-related issues.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

High TSPEAR levels in colorectal cancer predict worse outcomes.

High TSPEAR levels in colorectal cancer predict worse outcomes.

Nanocarriers can improve the effectiveness of herbal medicines in treating colorectal cancer.

Isotretinoin can raise CPK levels, so patients need monitoring, especially before surgery.

A thorough history and examination are crucial for diagnosing skin diseases, which affect up to a third of people. This includes details about skin lesions, medication, general health, lifestyle, family, and contacts, as well as examining the rash, hair, nails, and mucous membranes. Changes in hair and nails can also indicate other medical and skin disorders.

Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

A patient with Cronkhite-Canada Syndrome developed colon cancer that spread to the liver, showing the need for regular cancer checks in such patients.

Ripretinib is effective and safe for treating advanced GIST in Chinese patients, particularly for non-gastric GISTs.

A man had severe stomach issues after a dental treatment with Formacresol, which improved with a different medication.

A 60-year-old man with Cronkhite-Canada syndrome improved with treatment, but the condition has a high mortality rate and a risk of colorectal cancer.

Childhood cancer diagnosis leads to long-term physical and emotional health issues in parents.

A cancer patient's eyelashes grew excessively without other common side effects after taking the cancer drug erlotinib.

Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.

Oral paclitaxel plus encequidar improved tumor response and caused less neuropathy but more serious infections than intravenous paclitaxel.

The combination of gemcitabine and vinorelbine is effective and safe for treating elderly patients with advanced breast cancer previously treated with anthracyclines and taxanes.