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Protein composition greatly affects the function of keratin biomaterials.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Rice bran extract can potentially treat hair loss by promoting hair growth and increasing the number of hair follicles.

Supercritical CO2 extraction makes rice bran oil healthier and safer than traditional methods.

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

Blocking IL-17 signaling can delay skin aging and improve skin and hair health.

γδTregs may help treat autoimmune diseases like alopecia areata by promoting hair regrowth and reducing immune attacks.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

Non-immune dermal cells dominate, epidermal cells increase after day 9, and certain immune cells persist beyond inflammation in wound-induced hair follicle regeneration.

Rosemary oil can boost hair growth by increasing certain enzyme activities and cytokine expression.

Immune changes and specific genes contribute to male hair loss.

Fat cells help recruit healing cells and build skin structure during wound healing.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Cytotoxic T cells cause hair loss in chronic alopecia areata.

NK cells play a role in skin diseases like eczema and psoriasis.

Syndecan-1 is essential for maintaining skin fat and preventing cold stress.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.

New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

Alopecia areata severity and treatment response are linked to specific cytokine levels.

Trichloroethylene causes skin inflammation in mice by increasing certain immune proteins.