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The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Injected human hair follicle cells can create new, small hair follicles in skin cultures.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Decomposed tritiated thymidine is less accurate for DNA tracing, and hair changes can indicate malnutrition.

UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.

Chemotherapy can cause various skin problems, and recognizing them helps improve patient care.

HIV can cause unusual and severe skin problems that are hard to treat.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Chitosan-decorated polymersomes improve finasteride delivery for hair loss treatment.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Alefacept may effectively treat severe lichen planus, with patients showing significant improvement and no side effects.

Melatonin may reduce skin damage caused by X-rays in rats.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Tofacitinib was effective in treating hair loss in two patients with alopecia universalis.

A gene called HDAC9 might be a new factor in male-pattern baldness.

About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Despite progress in treatment, the exact cause of Alopecia areata is still unknown.