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Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Not having enough cystatin M/E protein causes less hair growth and dry skin.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.

Inactive hair follicle stem cells help prevent skin cancer.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Higher EULAR/ACR scores in SLE patients predict more organ damage.

Hair becomes gray and thin as we age, and while most hair loss in older people is due to genetics, there's a chance for gray hair to regain color under certain conditions.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

FGF12 is important for hair growth and could be targeted for hair loss treatment.

Notch signalling helps skin cells differentiate and prevents tumors.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Certain genes and nutrients like vitamin D, zinc, and omega fatty acids affect COVID-19 severity and infection risk.

New treatments and diagnostic methods for various animal skin conditions showed promising results.

Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.

Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.

Deleting the MAD2L1 gene is tolerated in certain mouse cancer models.

Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.

Disrupted stem cell signals in hairpoor mice cause hair loss.

A new genetic disorder caused by an ODC1 mutation can be treated with DFMO.

ODC1 gene mutations cause a neurodevelopmental disorder with large head size, hair loss, and facial abnormalities.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.