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The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.

Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Minoxidil activates hair growth by being sulfated by P-PST in the human liver.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.

Conductive hydrogels show promise for medical uses like healing wounds and tissue regeneration but need improvements in safety and stability.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

RANK-RANKL signaling is essential for hair growth and skin health.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Alopecia areata involves immune system imbalances that may lead to depression and anxiety.