29 citations,
May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
27 citations,
October 1999 in “Experimental and Molecular Pathology” Stump-tailed macaque best for researching hair loss causes and treatments.
October 2021 in “The Egyptian Journal of Hospital Medicine ” Combination therapies work better than single treatments for atrophic acne scars.
82 citations,
March 2016 in “Autoimmunity reviews” Animal models have helped understand hair loss from alopecia areata and find new treatments.
January 2016 in “Human & Experimental Toxicology” A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.
518 citations,
November 2014 in “Science” Skin grafting and wound treatment have improved, but we need more research to better understand wound healing and create more effective treatments.
December 2023 in “Regenerative therapy” miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
1 citations,
March 2023 in “Aggregate” A new hydrogel with micronized amnion helps achieve better, scar-free skin healing.
2 citations,
January 2017 in “AIMS cell and tissue engineering” Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.
133 citations,
July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
25 citations,
April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
6 citations,
June 2022 in “Frontiers in Bioengineering and Biotechnology” The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.
33 citations,
October 2013 in “PloS one” Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
75 citations,
October 2012 in “Journal of Investigative Dermatology” Alopecia areata can be triggered by specific immune cells without genetic or environmental factors.
45 citations,
June 2018 in “Frontiers in immunology” MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
48 citations,
September 2017 in “Frontiers in Bioscience” Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
132 citations,
June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
286 citations,
August 2007 in “Journal of Clinical Investigation” Alopecia areata is an autoimmune disease where T cells attack hair follicles.
1 citations,
January 2019 in “The International Journal of Lower Extremity Wounds” Artificial dermal template treatment can stimulate complete skin and hair follicle regrowth.
14 citations,
January 2021 in “Scientific Reports” Using micro skin tissue columns improves skin wound healing and reduces scarring.
52 citations,
February 2012 in “Plastic Surgery International” Skin grafting is a key procedure for repairing skin defects, with the success depending on the right graft choice, donor site management, and aftercare.
2 citations,
July 2013 in “Veterinary dermatology” Dog skin with hair loss, when transplanted to mice, regrew hair, suggesting the hair loss cause is likely body-wide, not skin-specific.
15 citations,
February 2011 in “Journal of Tissue Engineering and Regenerative Medicine” The best method for transplanting skin cells to regenerate hair follicles is the Hemi-vascularized sandwich method, as it produces more mature follicles and promotes hair growth.
March 2018 in “Cambridge University Press eBooks” Transplant patients face higher skin cancer risks due to immunosuppressive therapy, requiring careful skin health monitoring.
7 citations,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” T-cell reconstitution after thymus transplantation can cause hair whitening and loss.
6 citations,
April 2022 in “Journal of diabetes research” Type 2 diabetes slows down skin and hair renewal by blocking important stem cell activation in mice.
1 citations,
June 2023 in “Journal of Cellular and Molecular Medicine” The new method using gene-modified stem cells and a 3D printed scaffold improved skin repair in mice.
July 2023 in “Stem Cells Translational Medicine” Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.
12 citations,
September 2020 in “Stem cell research & therapy” Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.