329 citations
,
January 1997 in “Journal of the American Academy of Dermatology” This study reports that progressive frontal fibrosing alopecia, a distinct and gradually stabilizing form of lichen planopilaris affecting elderly women and often involving eyebrow hair loss, lacks effective treatments.
61 citations
,
January 2019 in “American Journal of Clinical Dermatology” This review discusses the potential causes and treatments for frontal fibrosing alopecia but reports no new clinical findings, highlighting the need for further research to understand its pathogenesis and develop validated treatments.
32 citations
,
September 2017 in “Journal of the American Academy of Dermatology” In this study, researchers reported that oral isotretinoin effectively treated facial papules in frontal fibrosing alopecia, with histopathologic findings suggesting the involvement of elastic fibers and sebaceous glands in papule formation beyond perifollicular inflammation.
17 citations
,
May 2013 in “Oral and Maxillofacial Surgery Clinics of North America” This article reviews the complex challenges of managing scalp and cranial deformities post-trauma or surgery, advocating for better multidisciplinary approaches to enhance outcomes, but reports no new results.
8 citations
,
October 2016 in “Actas Dermo-Sifiliográficas” This study found that men with frontal fibrosing alopecia exhibited more frequent facial papules, androgenetic alopecia, and body hair loss compared to women with the condition, and were generally older.
7 citations
,
January 2019 in “Australasian Journal of Dermatology” In this study, the CYP 21A2 gene p.V281L mutation was associated with an increased susceptibility to familial frontal fibrosing alopecia, suggesting an antigen-driven mechanism linked to certain human leukocyte antigen haplotypes.
2 citations
,
January 2023 in “Curēus” In this study, low-dose naltrexone significantly reduced erythema in patients with frontal fibrosing alopecia and lichen planopilaris after one year, but no significant improvements were seen in other symptoms.
January 2020 in “Revista da Sociedade Portuguesa de Dermatologia e Venereologia” This study reports that frontal fibrosing alopecia in Brazilian patients is common in postmenopausal women and often associated with hypothyroidism and facial irritation from cosmetic products.
May 2003 in “Journal of Investigative Dermatology” This article reviews the progress in hair biology research, including advancements in understanding androgen action, hair follicle stem cells, and autoimmune mechanisms in alopecia, and reports no new clinical results.
15 citations
,
March 2015 in “Facial plastic surgery” This article series reviews volumetric restoration techniques for different facial regions by expert authors, offering assessments of specific products but provides no new clinical results.
19 citations
,
September 2014 in “British Journal of Dermatology” This study found that topical minoxidil 5% foam was effective in promoting hair growth in both the frontal and vertex scalp for men with androgenetic alopecia.
6 citations
,
September 2019 in “Archives of Dermatological Research” In this study, researchers identified 32 differentially expressed genes involved in androgenetic alopecia, with down-regulated genes associated with Wnt and TGF-beta signaling and up-regulated genes linked to oxidative stress pathways.
33 citations
,
January 1997 in “Endocrinology” Testosterone was found to inhibit hair follicle epithelial cell proliferation in adult stumptailed macaques only when dermal papilla cells from bald scalps were present, and this effect was reversed by the antiandrogen RU 58841.
10 citations
,
February 2022 in “Epidemiologia” This study reported that about one-third of post-COVID-19 patients experienced long-term symptoms, with women, older individuals, smokers, and those with specific blood groups at higher risk for complications.
5 citations
,
April 2014 in “The American Journal of Dermatopathology” This article reports on a typical case of lichen planopilaris with foreign-body granulomas around hair shaft material, suggesting these may be an additional criterion for diagnosing late-stage LPP/FFA.
3 citations
,
December 2004 in “Aesthetic Surgery Journal” This narrative argues for the routine inclusion of hair restoration surgery in facial rejuvenation, noting the significant benefits for patients, but reports no new clinical results.
February 2021 in “Cureus” In this case report, the authors describe a rare presentation of alopecia areata mimicking frontal fibrosing alopecia, emphasizing the diagnostic value of trichoscopy and the need to consider alopecia areata in differential diagnoses.
129 citations
,
January 2009 in “International Journal of Trichology” This study found that trichoscopy criteria can distinguish female androgenic alopecia from chronic telogen effluvium, with specific features achieving 98% diagnostic specificity.
2 citations
,
September 2021 in “Anais Brasileiros de Dermatologia” Increased sunscreen use may be linked to frontal fibrosing alopecia in Hispanic females.
1 citations
,
October 2018 in “European Journal of Plastic Surgery” This study found that 2-hair follicular unit grafts were the most common grouping in hair transplant procedures, with frontal edema as the most frequent postoperative complication.
December 2023 in “JEADV Clinical Practice” This study found that dermoscopy of the axilla in patients with frontal fibrosing alopecia revealed significantly higher odds of brownish peripillary halos, suggesting a diagnostic clue for the condition in this region.
157 citations
,
July 2001 in “British Journal of Dermatology” In this study, the prevalence of androgenetic alopecia among Korean men and women was found to be lower than in caucasians, with Korean men showing more frontal hairline preservation and a higher incidence of 'female pattern' hair thinning.
125 citations
,
May 2007 in “Journal of The American Academy of Dermatology” This study describes the development of the BASP classification system, providing a universal and systematic approach for classifying pattern hair loss in both men and women.
39 citations
,
October 1967 in “British Journal of Dermatology” Hair loss in women often doesn't follow a pattern, isn't linked to age, may be genetic, and can be related to thyroid issues or other health factors.
37 citations
,
October 2015 in “Anais Brasileiros de Dermatologia” This study found diverse clinical presentations of lichen planopilaris, with classic lichen planopilaris being the most common, highlighting the importance of recognizing this variability for accurate diagnosis.
5 citations
,
November 2013 in “Case reports in dermatology” This case report details a 57-year-old woman with frontal fibrosing alopecia who developed hyperpigmentation after treatment with dutasteride and pimecrolimus, highlighting no previously reported hyperpigmentation association with this combination.
5 citations
,
August 2013 in “Facial plastic surgery clinics of North America” This article discusses managing extensive hair loss with limited transplant options and suggests a frontal forelock-type pattern is effective for both already bald men and younger patients at risk; it reports no new clinical results.
4 citations
,
January 2021 in “Postępy Dermatologii i Alergologii” This study found that hydroxychloroquine significantly reduced disease activity in women with frontal fibrosing alopecia and lichen planopilaris, particularly benefitting patients after 12 months of treatment.
4 citations
,
January 2019 in “Acta dermato-venereologica” This study found that women with frontal fibrosing alopecia have a significantly higher prevalence of rosacea compared to controls, particularly those with severe alopecia, and certain factors like perifollicular erythema, higher BMI, and lower progesterone levels were linked to increased rosacea risk.
4 citations
,
January 2016 in “Postepy Dermatologii I Alergologii” This article discusses various hair diseases and emphasizes their significant impact despite affecting a small area, but does not report new clinical findings.