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This study reports a case of a woman with Cushing's disease whose initial complaint was hair loss, a rare presenting symptom, despite multiple dermatological signs like easy bruising and violaceous striae being more indicative of the condition.

In this study, pregnant women with isolated hypothyroxinemia experienced more asthenia, dry skin, hair loss, fragile nails, vomiting, and anemia, suggesting a negative impact on pregnancy despite treatment.

In this study, researchers at the Hospital Militar Universitario “Dr. Carlos Arvelo” found that among children under five with severe malnutrition, skin pigmentation changes and extreme thinness were the most common signs.

This study found that the wild-derived mouse strain Mus pahari has fragile skin that separates at subdermal levels under moderate force, potentially due to altered extracellular matrix development.

This review discusses the effects of oestrogen on skin ageing and highlights the need for large-scale clinical trials to evaluate postmenopausal oestrogen use, reporting no new findings.

This chapter reviews various fungal skin diseases affecting cattle but does not report new research findings; it focuses on rare, inherited, and congenital conditions like follicular dysplasia and cutaneous asthenia.

In this animal study, treatment with Trachyspermum copticum seed extract significantly altered IL-1 and KGF/FGF-7 gene expression, improving dermatitis and hair growth in mice compared to controls and corticosteroids.

This review discusses the characteristics, impact, and management challenges of central centrifugal cicatricial alopecia and reports no new clinical findings, highlighting the need for further research and early detection strategies.

This study provides definitive evidence that a homozygous mutation in the DSC3 gene causes skin fragility and hypotrichosis in humans.

This chapter details the causes and diagnostic process of pediatric alopecia, including trichoscopic findings, but reports no new clinical results.

This case study describes a 14-year-old girl with pili annulati who had fragile hair, which may be due to cavities within the hair shafts as seen in electron microscopic examinations.

In this study, researchers found that the absence of type I or type II keratins in mice leads to severe skin barrier defects, highlighting keratins' crucial role in epidermal structure and function.

A man with Woolly Hair Syndrome had very curly, fragile hair, and doctors used a special scalp examination to diagnose him without invasive tests.

This study found that desmocollin 1 is crucial for strong adhesion and barrier maintenance in the mouse epidermis, with its absence leading to skin and hair issues resembling chronic dermatitis.

A gene deletion in DSG4 causes sparse hair in some Pakistani families.

In this case report, researchers describe a rare instance of bullous lupus presenting with severe esophageal involvement in a 42-year-old woman, highlighting the significant diagnostic and therapeutic challenges encountered in such cases despite successful treatment with immunosuppressive therapy.

This study identified four novel DSG4 mutations associated with monilethrix in 12 Jewish families, suggesting a recessive inheritance pattern and broader prevalence of DSG4-related hair disorders than previously recognized.

This study reports the first instance of skin autotomy in mammals, specifically in African spiny mice, and suggests they may possess a greater regenerative capacity than previously understood, possibly offering insights for regenerative medicine.

This article reviews advancements in burn care, emphasizing early wound excision's role in decreasing morbidity and mortality, but it reports no new clinical findings.

Skin changes can indicate starvation and nutritional deficiencies in anorexia nervosa.

This study found that overexpression of the mineralocorticoid receptor in a mouse model led to premature epidermal barrier development, keratinocyte apoptosis, and postnatal alopecia, indicating new roles for MR signaling in skin physiology.

This study investigated the histopathology of ectodermal dysplasia/skin fragility syndrome, identifying specific skin and hair abnormalities associated with PKP1 gene mutations in two young female patients.

This study found that topically delivering KGF-1 DNA plasmid increased epithelial thickness and skin strength, suggesting potential benefits for strengthening compromised skin.

This study found that negative pressure wound therapy combined with skin grafting is a feasible method for treating soft tissue and skin defects in cats, achieving a high graft take rate and satisfactory outcomes.

This chapter defines skin integrity as a blend of intact structural elements and adaptable functional capacity, highlighting its importance in maintaining skin health across various conditions but reports no new research findings.

This review discusses the impact of menopause-related oestrogen deficiency on skin ageing and suggests that oestrogen use may improve collagen and skin elasticity, but it reports no clinical trial results.

This study observed that pruritus and xerosis were the most common skin complaints among the geriatric population attending a dermatology clinic in Puducherry.

Hormones significantly affect skin health, with vitamin D playing a key role.

This review discusses the diverse roles and characteristics of epidermal and dermal stem cells in skin regeneration and aging, highlighting their potential applications in regenerative medicine and reports no new clinical results.

Obesity is linked to various skin problems and may increase the risk of skin cancer.