TLDR Epidermolysis bullosa is an inherited condition causing fragile skin with no cure, managed by wound care and experimental treatments show promise.
Epidermolysis bullosa (EB) is a collection of inherited disorders caused by mutations affecting the skin's structural protein, leading to skin and mucosal fragility, erosions, and/or blisters. The severity of skin and mucosal lesions can vary greatly depending on the subtype of EB. Currently, there is no definitive cure for EB, and management primarily involves supportive care, such as wound care and prevention of complications. Experimental therapies like gene therapy, cell-based therapy, and protein therapy have shown some potential in treating EB.
9 citations,
March 2012 in “Experimental dermatology” Natural gene therapy shows promise for treating skin disorders like epidermolysis bullosa.
32 citations,
April 2013 in “Anais Brasileiros de Dermatologia” The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.
69 citations,
June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
January 2020 in “Medical journal of clinical trials & case studies” A 37-year-old male with severe skin and internal issues has a rare inherited skin condition called dystrophic epidermolysis bullosa.
36 citations,
January 2012 in “International Journal of Trichology” Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.
