47 citations
,
January 1998 in “Molecular Carcinogenesis” This study observed that targeted expression of the neu oncogene in transgenic mice led to significant epidermal hyperplasia and a carcinoma-like appearance, suggesting a crucial role for erbB2 signaling in epidermal proliferation and carcinogenesis.
45 citations
,
November 2017 in “Biomaterials” This study demonstrated a method for large-scale preparation of self-sorted hair follicle germs in vitro, which successfully generated hair follicles when transplanted into the skin of nude mice.
39 citations
,
June 2012 in “Journal of Structural Biology” Disulfide bonds are crucial for hair structure during keratinization.
38 citations
,
January 2020 in “Journal of Experimental Botany” This study found that moderate water stress in rice plants induces rhizosheath formation, influenced by abscisic acid and auxin pathways, suggesting potential for breeding drought-resistant rice varieties.
33 citations
,
October 2006 in “European Journal of Immunology” This study found that CD44 and CD49d together enhance signaling pathways in lymphocytes in mice with alopecia areata, influencing their activation and function.
28 citations
,
August 2013 in “Hypertension” The authors concluded that diazoxide reduces undesirable side effects compared to minoxidil while increasing elastic fiber content and decreasing cell number in the aorta, suggesting potential suitability for treating vascular conditions with low arterial elastin and hypertension.
27 citations
,
October 1998 in “Differentiation” Basonuclin helps identify and track hair follicle development and cycling in mice.
18 citations
,
June 2018 in “Journal of Dental Research” This study found that during amelogenesis in Msx2 null mice, a dysfunctional enamel organ developed due to abnormal epithelial transformation and lacked proper enamel formation.
18 citations
,
January 2009 in “Experimental Dermatology” This study proposes that mammalian target of rapamycin (mTOR) may connect various signaling pathways in hair follicle tumor formation, offering a potential unified model for understanding these tumors.
17 citations
,
July 2019 in “Majalah Obat Tradisional” This study found that tannin effectively inhibits and degrades mono-species and polymicrobial biofilms, making it a potential candidate for antibiofilm treatments.
17 citations
,
March 2012 in “Journal of biological chemistry/The Journal of biological chemistry” In this study, researchers found that overexpression of the hairless protein in Hr mutant mice disrupts inner root sheath formation by downregulating Dlx3 and associated keratins in hair follicle development.
13 citations
,
December 2018 in “Development, Growth & Differentiation” This study found that male and female chicken feather morphology and color patterns can be extrinsically modified through molting and resetting the stem cell niche during regeneration.
12 citations
,
October 1947 in “Journal of the Society of Dyers and Colourists” This study found that treatment with mercuric acetate modifies the elastic properties of Lincoln wool fibers more rapidly than human hair, explaining the enhanced unshrinkable quality of wool under certain conditions.
11 citations
,
March 2014 in “Journal of Investigative Dermatology” In this study, basal cell carcinoma developed in Ptch-deficient mice only after chemical treatment, not skin wounding, suggesting a second unknown event is necessary for tumor formation.
11 citations
,
January 2014 in “The Journal of Clinical Endocrinology & Metabolism” This study suggests that estrogen synthesis from estrone sulfate significantly influences hair growth regulation, with variations based on the hair growth phase, gender, and age.
9 citations
,
January 2009 in “PubMed” This study found that finasteride treatment in men with benign prostate hyperplasia significantly altered steroid hormone profiles and may contribute to depressive symptoms by affecting neuroactive steroid levels.
7 citations
,
March 2002 in “AIDS” This case report presents an HIV-1 patient who experienced osteosclerosis and new bone formation potentially due to long-term indinavir therapy and concurrent use of vitamin A, with symptoms reducing after switching to nelfinavir.
5 citations
,
November 2023 in “Journal of Investigative Dermatology” This study observed that cutaneous microwounds created by fractional photothermolysis heal differently from typical wounds, displaying rapid re-epithelialization and limited inflammation, which may help reduce scar formation by delaying collagen remodeling and minimizing myofibroblast activation.
2 citations
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January 1995 in “Nihon Keshouhin Gijutsushakaishi/Journal of S C C./Nihon Keshouhin Gijutsushakai kaishi” This study found that treating permed hair with diethylene glycol monoethylether significantly reduced the formation of split ends, making it similar to untreated normal hair in terms of split ends generation.
1 citations
,
November 2022 in “Animals” This study found that differences in skin transcriptomes between juvenile and adult mink, as well as between black and white mink, suggest genes regulating hair color are active during early development rather than adulthood.
1 citations
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January 2021 in “Journal of dermatology & dermatologic surgery” In this study, researchers found no association between the use of oral isotretinoin at a standard dose and the development of milia in patients with moderate-to-severe acne vulgaris.
In this study, the researchers analyzed skin samples from Dun Mongolian horses to uncover molecular pathways linked to the "Bider" marking, identifying differential gene expression and several pigment-related signaling pathways that may play key roles in its formation.
January 2026 in “Beilstein Journal of Organic Chemistry” This study developed a metal-free method for synthesizing sulfinimidate esters, showcasing their potential as versatile intermediates for enantioselective bond formation under mild conditions.
September 2025 in “Development” In this study, deleting the transcriptional pause factor Nelfb in mouse preadipocyte lineages led to defective dermal fat formation and lethal outcomes, while interventions targeting Pparg could rescue adipocyte differentiation and promote dermal white adipose tissue formation, underscoring Nelfb's critical role in adipogenesis.
January 2025 in “Open Medicine” This study found that high-concentration cell-free adipose extract effectively reduced collagen deposition and blood vessel formation in a rabbit ear model, showing promise for preventing and treating hypertrophic scars.
January 2025 in “Advances in Dermatology and Allergology” This study found that the Polish version of the AA-QLI questionnaire is a reliable and internally consistent tool for assessing health-related quality of life in Polish-speaking patients with alopecia areata.
November 2022 in “Journal of Investigative Dermatology” This study found that removing autophagy in keratinocytes led to increased skin inflammation, higher risk of skin tumors, and early hair follicle activation in mice.
January 2020 in “Advanced ultrasound in diagnosis and therapy” This case report highlights a misdiagnosis of an epidermoid cyst as a dermoid cyst using ultrasound, suggesting that specific ultrasound features can improve diagnostic accuracy for skin lesions.
January 2013 in “Sen'i Gakkaishi” This study found that microfibrils play a crucial role in shaping permanent waves by thioglycolic acid, and treating damaged hair with hydrolyzed keratin improved both waving efficiency and hair damage.
January 1998 in “Differentiation” Basonuclin is crucial for hair follicle development and cycling in mice.