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Effective PCOS treatments require targeting specific signaling pathways.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.

Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.

Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

FOXC1 boosts SFRP1 in hair loss, suggesting new treatments.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Seborrheic dermatitis is influenced by diet, genetics, and psychological factors.

Mutant mice help researchers understand hair growth and related genetic factors.

New drugs for heart disease may be developed from molecules secreted by stem cells.

Reducing FOXA2 in skin cells lowers their ability to grow hair.

Acne is a common skin condition that can be influenced by diet, lifestyle, and hormones, and requires a treatment approach that includes psychological considerations.

Genetic mutations can affect female sexual development, requiring personalized medical care.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

Plant extracts may help prevent or reverse hair graying.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.

Our microbiome may affect the development of the hair loss condition Alopecia Areata, but more research is needed to understand this relationship.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.

Certain genes affect udder shape in Holstein cows, important for health and milk production.