10 citations,
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.
October 2020 in “Our Dermatology Online” Chronic bacterial infections of hair follicles can cause ongoing skin inflammation.
[object Object] 59 citations,
October 2012 in “Pharmaceutical Research” Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.
71 citations,
March 1995 in “Journal of The American Academy of Dermatology” Using both vertical and transverse sections for alopecia biopsies improves diagnosis without extra cost.
29 citations,
January 2007 in “Dermatologic Clinics” Photodynamic Therapy is an effective treatment for mild to severe acne.
11 citations,
September 1996 in “Neuroscience letters” Adding fetal calf serum helps Merkel cells survive and change shape.
2 citations,
September 2016 in “Journal of Dermatological Science” Squarticles, tiny particles made from sebum-derived lipids, can effectively deliver minoxidil, a hair growth drug, directly to hair follicles and skin cells, with less skin penetration and more tolerability.
1 citations,
July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
1 citations,
January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.
April 2016 in “Journal of Investigative Dermatology” A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.
March 2004 in “Journal of The American Academy of Dermatology” Patients with SLE experienced non-scarring hair loss with fewer hair follicles, and DIF did not help identify lupus.
March 2004 in “Journal of The American Academy of Dermatology” Women with lupus experienced non-scarring hair loss with fewer hair follicles, and the test for lupus in hair was not helpful.
499 citations,
September 2011 in “Cell” Fat-related cells are important for initiating hair growth.
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
162 citations,
August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The new "differential stripping" method effectively measures how much substance gets into hair follicles.
143 citations,
October 2008 in “Journal of The American Academy of Dermatology” Comma hairs are a specific sign of tinea capitis when viewed with videodermatoscopy.
131 citations,
July 2009 in “Experimental Dermatology” The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
122 citations,
April 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.
109 citations,
March 2011 in “Journal of controlled release” New micelle solutions greatly improve skin delivery of certain antifungal drugs.
96 citations,
April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
59 citations,
July 2015 in “Journal of innovative optical health sciences/Journal of innovation in optical health science” Nanoparticles around 600-700 nm can effectively enter and stay in hair follicles for days, which may help in delivering drugs to specific cells.
[object Object] 56 citations,
July 2005 in “Journal of The American Academy of Dermatology” Using both vertical and transverse sections gives a better diagnosis of alopecia than using one method alone.
53 citations,
January 2009 in “Journal of Investigative Dermatology” UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.
51 citations,
May 2019 in “Biomaterials” Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.
42 citations,
October 2012 in “Dermatologic Clinics” Trichoscopy is a useful tool for diagnosing different hair and scalp diseases without surgery.
39 citations,
November 2013 in “European journal of pharmaceutics and biopharmaceutics” Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.
38 citations,
August 2005 in “Veterinary dermatology” A disease causing skin issues in young adult German short-haired pointers is hereditary, with most affected dogs not responding to treatment.
37 citations,
November 2003 in “Veterinary pathology” Hair loss in mice starts with immune cells damaging hair roots before it becomes visible.
36 citations,
February 2018 in “British Journal of Dermatology” Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.
31 citations,
April 1999 in “Dermatologic Clinics” Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.