June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a comprehensive Ayurvedic treatment protocol was shown to effectively improve symptoms of Indralupta, a condition similar to alopecia areata, by reducing patch size, increasing hair density, and restoring follicular activity, without adverse effects.
February 2026 in “American Scientific Research Journal for Engineering, Technology, and Sciences (Global Society of Scientific Research and Researchers)” This study analyzed gray hair, revealing that it differs from pigmented hair in follicular activity, oxidative balance, and structure, impacting coloring processes and necessitating adapted techniques to maintain hair quality.
In this study, personalized PRP therapy significantly increased hair density and diameter in a patient with androgenetic alopecia, highlighting its potential benefit but emphasizing the need for broader clinical trials.
In this randomized controlled trial at Bolan Medical Complex Hospital, researchers observed that liquid nitrogen cryotherapy increased hair regrowth by 60% in alopecia areata patients, significantly outperforming alternative treatments, which achieved 40% regrowth.
February 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A hair test can accurately predict if a person with hair loss will respond to minoxidil treatment.
18 citations
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March 2015 in “Journal of Investigative Dermatology” In this study, silencing BMAL1 and PER1 genes increased melanogenic activity in follicular and epidermal melanocytes, suggesting that peripheral circadian clocks may regulate melanin pigmentation.
November 2025 in “SKIN The Journal of Cutaneous Medicine” This review highlights the potential benefits of low-level light therapy for treating various alopecias, with reported improvements in hair density and count, especially when combined with minoxidil or finasteride, but it offers no new clinical results.
67 citations
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August 2013 in “International Journal of Cosmetic Science” This review discusses the role of oxidative stress in hair greying and suggests that understanding melanocyte susceptibility at different follicular locations may help develop therapies for preventing and reversing the process; it reports no new experimental results.
15 citations
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August 2006 in “Journal of Cutaneous Pathology” This study found that diffuse alopecia in HIV-1-infected patients is characterized by higher rates of follicular stem cell apoptosis compared to controls, suggesting a hair cycle disturbance associated with the infection.
7 citations
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March 1990 in “Pigment Cell Research” This animal study observed that while topical MBEH and intraperitoneal phenol induced hair graying in eumelanic mice, they had little effect on pheomelanic mice, and amcinonide reduced certain epidermal melanocytes in both.
4 citations
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October 2021 in “International Journal of Cosmetic Science” This study found that C. japonicum flower extract significantly increased melanin content and cellular activity in human melanocytes and may improve follicular depigmentation and vitiligo through cAMP signaling.
1 citations
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May 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” In laboratory studies on mice, Abstract UT-018, a stem cell chemoattractant formulation, was reported to significantly enhance wound healing and promote hair regeneration through mechanisms involving improved tissue formation, collagen organization, and follicular development.
July 2026 in “Skin Appendage Disorders” This review highlights that poor therapeutic responses in female pattern hair loss involve multiple factors, including pharmacogenetic influences and comorbidities. It suggests a framework to improve outcomes by identifying the primary contributors and using personalized treatment strategies.
April 2025 in “Pharmaceutics” This study examined three olive oil formulations of baricitinib for topical delivery in treating alopecia areata, finding that Oil A showed the highest skin retention and maintained skin integrity without irritation, suggesting its potential for further investigation.
September 2021 in “CRC Press eBooks” This review discusses dissecting cellulitis of the scalp and reports no new clinical findings.
March 2021 in “Research Square (Research Square)” This study found that stress is likely the main cause of symmetrical alopecia in Formosan macaques, with higher stress hormone levels observed in affected individuals.
August 2021 in “Journal of The American Academy of Dermatology” This article discusses the androgenicity of progestins used in hormonal contraceptives and its potential impact on female pattern hair loss, but reports no new clinical findings.
9 citations
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August 2019 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil activation by hair enzymes predicts treatment success for female hair loss.
51 citations
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May 2019 in “Biomaterials” This study developed a method for generating germ-like tissues called bbHFGs, which efficiently promoted hair follicle formation in mice, potentially advancing hair regenerative medicine applications.
April 2026 in “BMC Biotechnology” This study evaluated a novel synthetic cell-penetrating peptide, DualPep-ALO, finding it promotes hair growth by enhancing follicle cell proliferation, activating regenerative pathways, and reducing inflammation and oxidative stress in vitro and ex vivo, suggesting a promising new topical treatment for hair loss that rivals minoxidil.
April 2024 in “Molecules/Molecules online/Molecules annual” This review discusses the potential of P. polyphylla saponins to treat acne through antibacterial, anti-inflammatory, immunomodulatory, and antioxidant effects, noting that acne's complex pathogenesis makes this line of research promising for future studies.
April 2022 in “Journal of Investigative Dermatology” This paper presents an interactive quiz related to a study by Deng et al. (2022) in the Journal of Investigative Dermatology, examining androgen receptor-mediated paracrine signaling in androgenetic alopecia, but it provides no new clinical findings.
January 2014 in “Journal of Pharmaceutical Negative Results” This study found that the ethanolic extracts of G. glabra and Z. mauritiana roots did not prevent androgenic alopecia in a testosterone-induced animal model.
February 2026 in “Cureus” This case report suggests that crisaborole may be an effective alternative treatment for alopecia areata in pediatric patients, showing significant hair regrowth after two weeks in a 10-year-old girl.
February 2026 in “Journal of Korea Society of Ingrielogy” This review discusses the potential immuno-regenerative effects of polydioxanone threads in hair loss treatment, focusing on tissue responses and immune modulation, but does not report clinical results.
January 2026 in “Preprints.org” This review highlights recent advancements in nanotechnology-based approaches for treating androgenetic alopecia, focusing on enhancing drug delivery to hair follicles, controlled release, and follicular microenvironment modulation, while addressing safety, manufacturing, and regulatory challenges for clinical application.
February 2025 in “Journal of the European Academy of Dermatology and Venereology” In this study, researchers found that mogamulizumab-associated rashes and alopecia are common in patients treated for mycosis fungoides and Sézary syndrome and may be linked with a good treatment response.
9 citations
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January 2013 in “BioMed research international” This article suggests targeting the water activity within pilosebaceous follicles using biocompatible solutes like xylose and sucrose as a new potential topical treatment for acne.
103 citations
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April 2005 in “Experimental dermatology” This study found that PGF2alpha analogues and PGE2 stimulated hair follicle activity in mice, with PGF2alpha analogues also linked to potential side effects like poliosis when used as eye treatments.
64 citations
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January 2009 in “The International journal of developmental biology” This study found that intra-follicular Wnt signaling and dermal BMP signaling oscillate differently during hair cycling in mice, affecting hair wave propagation and phases of hair growth.