Contraception Progestin Type and Female Pattern Hair Loss

August 2021 in “ Journal of The American Academy of Dermatology ”

Kelly E. Flanagan, James T. Pathoulas, Chloe J. Walker, Laura J. Burns, Isa Pupo Wiss, Maryanne M. Senna

progestin female pattern hair loss FPHL androgens follicular growth phase miniaturization of hair follicles first-generation progestins androgen activity antiandrogenic progestins hair miniaturization antiandrogens

TLDR Newer contraceptives with less androgenic progestins may reduce female hair loss.

The document discussed the relationship between different types of progestins in hormonal contraceptives and female pattern hair loss (FPHL). It highlighted that androgens are believed to play a role in FPHL by shortening the follicular growth phase and causing miniaturization of hair follicles. The study noted that first-generation progestins have the highest androgen activity, while newer generations have progressively less androgenic activity, with some newer progestins being antiandrogenic. This suggests that the type of progestin in contraceptives could influence the severity of FPHL.

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Contraception Progestin Type and Female Pattern Hair Loss

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