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    Glossary Follicles

    Follicles are small, tubular structures in the skin that house hair roots and are essential for hair growth. Each follicle goes through a cycle of growth, rest, and shedding, which is crucial for maintaining healthy hair. In the context of hair loss, the health and function of hair follicles are significant, as conditions like androgenetic alopecia can lead to miniaturization of follicles, resulting in thinner hair and eventual hair loss. Key distinguishing characteristics of follicles include their ability to regenerate and their varying sizes and shapes depending on the hair type they produce.

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    1. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001 · 949 citations
    2. Control of hair growth and follicle size by VEGF-mediated angiogenesis Journal of Clinical Investigation · 2001 · 520 citations
    3. Induction of follicle formation and hair growth by vibrissa dermal papillae implanted into rat ear wounds: vibrissa-type fibres are specified Development · 1992 · 125 citations
    4. Biology of the wool follicle: an excursion into a unique tissue interaction system waiting to be re‐discovered Experimental Dermatology · 2006 · 117 citations
    5. Expression patterns of keratin intermediate filament and keratin associated protein genes in wool follicles Differentiation · 2009 · 95 citations
    6. Epidermal growth factor delays the development of the epidermis and hair follicles of mice during growth of the first coat The Anatomical Record · 1983 · 72 citations
    7. Structure and expression of genes for a class of cysteine-rich proteins of the cuticle layers of differentiating wool and hair follicles. 1990 · 67 citations
    8. Hair matrix germinative epidermal cells confer follicle-inducing capabilities on dermal sheath and high passage papilla cells Development · 1996 · 61 citations
    9. The chemokine SDF-1/CXCL12 regulates the migration of melanocyte progenitors in mouse hair follicles Differentiation · 2009 · 57 citations
    10. Growth of secondary hair follicles of the Cashmere goat in vitro and their response to prolactin and melatonin. PubMed · 1994 · 56 citations
    11. Cell Movement in the Hair Follicle Dermis – More Than a Two-Way Street? Journal of Investigative Dermatology · 2003 · 47 citations
    12. Expression of the Intermediate Filament Keratin Gene,K15,in the Basal Cell Layers of Epithelia and the Hair Follicle Experimental Cell Research · 1998 · 46 citations
    13. Therapeutic Potential of Stem Cells in Follicle Regeneration Stem Cells International · 2018 · 45 citations
    14. Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells Molecular biology of the cell · 2008 · 43 citations
    15. Nevus lipomatosus cutaneous superficialis with folliculosebaceous cystic hamartoma Journal of the American Academy of Dermatology · 2007 · 31 citations
    16. Apoptosis in follicles of individuals with female pattern hair loss is associated with perifollicular microinflammation International Journal of Cosmetic Science · 2016 · 30 citations
    17. New Methodology and Instrumentation for Follicular Unit Extraction: Lower Follicle Transection Rates and Expanded Patient Candidacy Dermatologic Surgery · 2008 · 30 citations
    18. Expression of morphogens during human follicle development in vivo and a model for studying follicle morphogenesis in vitro 1993 · 29 citations
    19. The eyelash follicle features and anomalies: A review Journal of optometry · 2018 · 27 citations
    20. Identification of Differentially Expressed Genes During a Wool Follicle Growth Cycle Induced by Prolactin Journal of Investigative Dermatology · 1999 · 26 citations
    21. Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state Developmental cell · 2022 · 25 citations
    22. Expression of the heat shock protein-27 in the adult human scalp skin and hair follicle: Hair cycle–dependent changes Journal of the American Academy of Dermatology · 2006 · 24 citations
    23. Review of Human Hair Follicle Biology: Dynamics of Niches and Stem Cell Regulation for Possible Therapeutic Hair Stimulation for Plastic Surgeons Aesthetic Plastic Surgery · 2018 · 22 citations
    24. Ultrastructural abnormalities in the dermal papillae of both lesional and clinically normal follicles from alopecia areata scalps British Journal of Dermatology · 1996 · 19 citations
    25. Dermal-epidermal interactions—follicle-derived cell populations in the study of hair-growth mechanisms 1993 · 19 citations
    26. Seasonal changes in the morphology of wool follicles in Finewool and Strongwool Merino strains grazing at different stocking rates in southern Australia Australian Journal of Agricultural Research · 1997 · 17 citations
    27. Reduction in wool follicles prior to birth in Merino sheep Reproduction Fertility and Development · 1999 · 15 citations
    28. Folliculosebaceous cystic hamartoma with hair shaft fragments. PubMed · 2005 · 14 citations
    29. Accuracy of anti-Müllerian hormone and total follicles count to diagnose polycystic ovary syndrome in reproductive women Taiwanese Journal of Obstetrics & Gynecology · 2018 · 13 citations
    30. The <i>In Vitro</i> Use of the Hair Follicle Closure Technique to Study the Follicular and Percutaneous Permeation of Topically Applied Drugs ATLA. Alternatives to laboratory animals · 2012 · 12 citations